ArticleBMC genomics2021
Genome-wide identification of the 14-3-3 gene family and its participation in floral transition by interacting with TFL1/FT in apple.
Article in BMC genomics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 43 citations in OpenAlex.
- Genome-wide transcriptional analysis of 14-3-3 genes in Paulownia fortunei under abiotic and biotic stresses.BMC plant biology · 2026Article
- Genome-Wide Identification and Characterization of thePlants (Basel, Switzerland) · 2026Article
- Article
- Genomic identification of theMolecular breeding : new strategies in plant improvement · 2025Article
- Construction of Shoot Apical Meristem cDNA Yeast Library ofCurrent issues in molecular biology · 2024Article
- Functional Characterization of the 14-3-3 Gene Family in Alfalfa and the Role ofInternational journal of molecular sciences · 2024Article
- Transcriptome-Based Identification of Candidate Flowering-Associated Genes of Blueberry in a Plant Factory with Artificial Lighting (PFAL) under Short-Day-Length Conditions.International journal of molecular sciences · 2024Article
- Molecular Mechanisms of Seasonal Gene Expression in Trees.International journal of molecular sciences · 2024Review
- Restructuring plant types for developing tailor-made crops.Plant biotechnology journal · 2023Review
- Article
- The apple 14-3-3 geneFrontiers in plant science · 2023Article
- Genome-Wide Identification and Expression Analysis of the 14-3-3 (TFT) Gene Family in Tomato, and the Role ofPlants (Basel, Switzerland) · 2022Article
- Genome-wide identification and gene expression analysis of the 14-3-3 gene family in potato (Solanum tuberosum L.).BMC genomics · 2022Article
- Identification of the 14-3-3 Gene Family in Bamboo and Characterization ofInternational journal of molecular sciences · 2022Article
- Genome-Wide Identification and Expression Analysis of theInternational journal of molecular sciences · 2022Article
- Genome-Wide Identification ofFrontiers in plant science · 2022Article
- Genome-wide analysis of the G-box regulating factors protein family reveals its roles in response toFrontiers in plant science · 2022Article
- Evolution of 14-3-3 Proteins in Angiosperm Plants: Recurring Gene Duplication and Loss.Plants (Basel, Switzerland) · 2021Article
- Identification of apple TFL1-interacting proteins uncovers an expanded flowering network.Plant cell reports · 2021Article
- Genome-Wide Identification and Analysis of theGenes · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundApple (Malus domestica Borkh.) is a popular cultivated fruit crop with high economic value in China. Apple floral transition is an important process but liable to be affected by various environmental factors. The 14-3-3 proteins are involved in regulating diverse biological processes in plants, and some 14-3-3 members play vital roles in flowering. However, little information was available about the 14-3-3 members in apple.
resultsIn the current study, we identified eighteen 14-3-3 gene family members from the apple genome database, designated MdGF14a to MdGF14r. The isoforms possess a conserved core region comprising nine antiparallel α-helices and divergent N and C termini. According to their structural and phylogenetic features, Md14-3-3 proteins could be classified into two major evolutionary branches, the epsilon (ɛ) group and the non-epsilon (non-ɛ) group. Moreover, expression profiles derived from transcriptome data and quantitative real-time reverse transcription PCR analysis showed diverse expression patterns of Md14-3-3 genes in various tissues and in response to different sugars and hormone treatments during the floral transition phase. Four Md14-3-3 isoforms (MdGF14a, MdGF14d, MdGF14i, and MdGF14j) exhibiting prominent transcriptional responses to sugars and hormones were selected for further investigation. Furthermore, yeast two-hybrid and bimolecular fluorescence complementation experiments showed that the four Md14-3-3 proteins interact with key floral integrators, MdTFL1 (TERMINAL FLOWER1) and MdFT (FLOWERING LOCUS T). Subcellular localization of four selected Md14-3-3 proteins demonstrated their localization in both the cytoplasm and nucleus.
conclusionWe identified the Md14-3-3 s family in apple comprehensively. Certain Md14-3-3 genes are expressed predominantly during the apple floral transition stage, and may participate in the regulation of flowering through association with flower control genes. Our results provide a preliminary framework for further investigation into the roles of Md14-3-3 s in floral transition.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.