Evidence map›Paper›PMID 33419253›Full record

ArticleInternational journal of molecular sciences2020

The Cell-Free Expression of MiR200 Family Members Correlates with Estrogen Sensitivity in Human Epithelial Ovarian Cells.

Éva Márton, Alexandra Varga, Lajos Széles, Lóránd Göczi, András Penyige, Bálint Nagy, Melinda Szilágyi

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Éva MártonDepartment of Human Genetics, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Hungary.
Alexandra VargaDepartment of Human Genetics, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Hungary.
Lajos SzélesDepartment of Human Genetics, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Hungary.
Lóránd GöcziDepartment of Human Genetics, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Hungary.
András PenyigeDepartment of Human Genetics, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Hungary.ORCID 0000-0002-1993-2014
Bálint NagyDepartment of Human Genetics, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Hungary.ORCID 0000-0002-0295-185X
Melinda SzilágyiDepartment of Human Genetics, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Hungary.ORCID 0000-0002-0316-2553
University of Debrecen · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exposure to physiological estrogens or xenoestrogens (e.g., zearalenone or bisphenol A) increases the risk for cancer. However, little information is available on their significance in ovarian cancer. We present a comprehensive study on the effect of estradiol, zearalenone and bisphenol A on the phenotype, mRNA, intracellular and cell-free miRNA expression of human epithelial ovarian cell lines. Estrogens induced a comparable effect on the rate of cell proliferation and migration as well as on the expression of estrogen-responsive genes (

Indexed as

Biomarkers, TumorCadherinsCarcinoma, Ovarian EpithelialCell Line, TumorCell MovementCell ProliferationEndodeoxyribonucleasesEpithelial-Mesenchymal TransitionEstradiolEstrogen Receptor alphaEstrogensFemaleGene Expression Regulation, NeoplasticHumansIntracellular Signaling Peptides and ProteinsMicroRNAsBiomarkers, TumorCadherinsDEPTOR protein, humanEndodeoxyribonucleasesESR1 protein, humanEstradiolEstrogen Receptor alphaEstrogensGREB1 protein, humanIntracellular Signaling Peptides and ProteinsMicroRNAsMIRN200 microRNA, humanNeoplasm ProteinsRBBP8 protein, humanRNA, MessengerZEB1 protein, humanZinc Finger E-box-Binding Homeobox 1bisphenol Acell-free miRNAEMTestrogenestrogen receptormiR200miR203aovarian cancerzeralenone

Identifiers

PMID33419253
PMCPMC7766742
OpenAlexW3113800408

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.