Evidence map›Paper›PMID 33419150›Full record

ArticleViruses2021

A Nanoparticle-Based Trivalent Vaccine Targeting the Glycan Binding VP8* Domains of Rotaviruses.

Ming Xia, Pengwei Huang, Xi Jiang, Ming Tan

Abstract read
In one paragraph

Article in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. EngineeringVaccines · 2024
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. The αTSR Domain ofInternational journal of nanomedicine · 2023
    Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ming XiaDivision of Infectious Diseases, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.
Pengwei HuangDivision of Infectious Diseases, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.
Xi JiangDivision of Infectious Diseases, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.
Ming TanDivision of Infectious Diseases, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.ORCID 0000-0002-6489-5507

Funding

LCenter for Clinical and Translational Science and TrainingUL1TR001425 · NCATS · UNIVERSITY OF CINCINNATI · PI HEUBI, JAMES E., KISSELA, BRETT M · 2015 to 2024
$37.5M
Stem Cell/Organoid and Genome Editing CoreP30DK078392 · NIDDK · CINCINNATI CHILDRENS HOSP MED CTR · PI Alexander Miethke · 2007 to 2026
$24.4M
A Nanoparticle-Based Multivalent Rotavirus VaccineR56AI148426 · NIAID · CINCINNATI CHILDRENS HOSP MED CTR · PI TAN, MING · 2020 to 2020
$626k
NCATS NIH HHS UL1 TR001425NIAID NIH HHS R56 AI148426NIDDK NIH HHS P30 DK078392
6 · The paper itself

Abstract

Rotavirus causes severe gastroenteritis in children. Although vaccines are implemented, rotavirus-related diarrhea still claims ~200,000 lives annually worldwide, mainly in low-income settings, pointing to a need for improved vaccine tactics. To meet such a public health need, a P

Indexed as

AnimalsAntibodies, NeutralizingAntibodies, ViralMiceMice, Inbred BALB CNanoparticlesPolysaccharidesRNA-Binding ProteinsRotavirusRotavirus InfectionsRotavirus VaccinesViral Nonstructural ProteinsAntibodies, NeutralizingAntibodies, ViralNS35 protein, rotavirusPolysaccharidesRNA-Binding ProteinsRotavirus VaccinesViral Nonstructural Proteinsnon-replicating rotavirus vaccinenorovirus P domainP24-VP8* nanoparticlerotavirusrotavirus vaccinerotavirus VP8*

Identifiers

PMID33419150
PMCPMC7825513

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.