Evidence map›Paper›PMID 33419128›Full record

ArticleInternational journal of environmental research and public health2021

Prevalence of Hyperuricemia and the Use of Allopurinol in Older Poles-Results from a Population-Based PolSenior Study.

Mateusz Winder, Aleksander J Owczarek, Małgorzata Mossakowska, Katarzyna Broczek, Tomasz Grodzicki, Łukasz Wierucki, Jerzy Chudek

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 31 citations in OpenAlex.

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  9. Acute oral toxicity assessment and anti-hyperuricemic activity ofSaudi journal of biological sciences · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Mateusz WinderDepartment of Internal Medicine and Oncological Chemotherapy, Medical University of Silesia, 40-029 Katowice, Poland.ORCID 0000-0003-3175-5660
Aleksander J OwczarekDepartment of Statistics, Department of Instrumental Analysis, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia, 41-200 Katowice, Poland.ORCID 0000-0003-1179-6932
Małgorzata MossakowskaInternational Institute of Molecular and Cell Biology, 02-109 Warsaw, Poland.ORCID 0000-0002-9340-3188
Katarzyna BroczekDepartment of Geriatrics, Medical University of Warsaw, 02-007 Warsaw, Poland.
Tomasz GrodzickiDepartment of Internal Medicine and Gerontology, Jagiellonian University Medical College, 31-531 Krakow, Poland.ORCID 0000-0003-0159-4915
Łukasz WieruckiDepartment of Preventive Medicine and Education, Medical University of Gdańsk, 80-210 Gdansk, Poland.ORCID 0000-0003-2995-6180
Jerzy ChudekDepartment of Internal Medicine and Oncological Chemotherapy, Medical University of Silesia, 40-029 Katowice, Poland.ORCID 0000-0002-6367-7794
Medical University of Silesia · PLGdańsk Medical University · PLInternational Institute of Molecular and Cell Biology · PLJagiellonian University · PLMedical University of Warsaw · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOur study analyzes the frequency and risk factors of hyperuricemia and the use of allopurinol in a representative cohort of the older Polish adult population.

methodsThe analysis was a part of a cross-sectional PolSenior study on aging in Poland. The complete medication data were available in 4873 out of 4979 community dwelling respondents aged 65 and over. Serum uric acid concentrations were evaluated in 4028 participants (80.9% of the cohort).

resultsHyperuricemia was observed in 28.2% of women and 24.7% of men. Ten risk factors of hyperuricemia were selected based on multivariable LASSO logistic regression analysis. Nine factors showed significant odds ratios: eGFR < 60 mL/min/1.73 m

conclusionsHyperuricemia was present in 23.1% (95% CI: 21.8-24.4) of the older Polish population. The frequency of hyperuricemia increases with age, reaching 30.5% in men and 33.7% in women aged 90 years or more. Chronic kidney disease, obesity, heart failure, hypertriglyceridemia, and the use of diuretics were the strongest risk factors for hyperuricemia in older adults. The treatment with allopurinol was ineffective in more than half of participants.

Indexed as

AllopurinolHyperuricemiaAgedAged, 80 and overCross-Sectional StudiesFemaleHumansMalePolandPrevalenceRisk FactorsUric AcidAllopurinolUric Acidallopurinolelderlyhyperuricemiaprevalence

Identifiers

PMID33419128
PMCPMC7825523
OpenAlexW3120076978

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.