Evidence map›Paper›PMID 33419054›Full record

ArticleNutrients2021

Application of

Leónides Fernández, Irma Castro, Rebeca Arroyo, Claudio Alba, David Beltrán, Juan M Rodríguez

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06290518 (Modulation of the Reproductive Microbiota as a Strategy to Increase Rates of Reproductive Success in Couples With Infertility of Unknown Origin), which is not on this map. Cited by 23 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 4 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06290518 nacompletednot on this map

Modulation of the Reproductive Microbiota as a Strategy to Increase Rates of Reproductive Success in Couples With Infertility of Unknown Origin

TypeinterventionalSponsorBiosearch S.A.Ran2020 to 2024Enrolled72ConditionsInfertility UnexplainedArmsLigilactobacillus salivarius CECT5713, Placebo
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 4 syntheses or guidelines pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Nutrients · 2025
    Trial
  6. Trial
  7. Review
  8. Use ofFoods (Basel, Switzerland) · 2026
    Article
  9. Review
  10. All Properties of Infertility Microbiome in a Review Article.Journal of clinical laboratory analysis · 2025
    Review
  11. Review
  12. Understanding the Associations of Urogenital Microbiomes With Fertility and In Vitro Fertilization.American journal of reproductive immunology (New York, N.Y. : 1989) · 2025
    Review
  13. Nutrients · 2025
    Article
  14. Review
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Leónides FernándezDepartment of Galenic Pharmacy and Food Technology, Complutense University of Madrid, 28040 Madrid, Spain.ORCID 0000-0003-2380-0767
Irma CastroDepartment of Nutrition and Food Science, Complutense University of Madrid, 28040 Madrid, Spain.ORCID 0000-0002-5605-3422
Rebeca ArroyoDepartment of Nutrition and Food Science, Complutense University of Madrid, 28040 Madrid, Spain.
Claudio AlbaDepartment of Nutrition and Food Science, Complutense University of Madrid, 28040 Madrid, Spain.
David BeltránCentro de Diagnóstico Médico, Ayuntamiento de Madrid, 28006 Madrid, Spain.
Juan M RodríguezDepartment of Nutrition and Food Science, Complutense University of Madrid, 28040 Madrid, Spain.ORCID 0000-0002-1285-9686
Universidad Complutense de Madrid · ESAyuntamiento de Madrid · ES

Funding

Biosearch Life Research contrat
6 · The paper itself

Abstract

In this study, the cervicovaginal environment of women with reproductive failure (repetitive abortion, infertility of unknown origin) was assessed and compared to that of healthy fertile women. Subsequently, the ability of

Indexed as

Abortion, SpontaneousInfertilityAdaptor Proteins, Signal TransducingAdministration, OralAdultEcosystemFemaleHumansHydrogen-Ion ConcentrationImmunologic FactorsLactobacillusMiddle AgedPregnancyProbioticsVaginaAdaptor Proteins, Signal TransducingImmunologic FactorsTAB3 protein, humanimplantation failureinfertilityLactobacillus salivariusprobioticsrepetitive abortionTGF-βvaginal microbiomeVEGF

Identifiers

PMID33419054
PMCPMC7825435
OpenAlexW3120752322

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.