Evidence map›Paper›PMID 33419041›Full record

ArticleToxins2021

Transmission of Zearalenone, Deoxynivalenol, and Their Derivatives from Sows to Piglets during Lactation.

Xandra Benthem de Grave, Janine Saltzmann, Julia Laurain, Maria A Rodriguez, Francesc Molist, Sven Dänicke, Regiane R Santos

Open access · goldAbstract readRandomized Controlled Trial, Veterinary
In one paragraph

Article in Toxins, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Urinary mycoestrogens and gestational weight gain in the UPSIDE pregnancy cohort.Environmental health : a global access science source · 2024
    Article
  3. Review
  4. Article
  5. Effects of the Inclusion of Dietary Bitter Gourd (Animals : an open access journal from MDPI · 2023
    Article
  6. Article
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Xandra Benthem de GraveSchothorst Feed Research, 8218 NA Lelystad, The Netherlands.
Janine SaltzmannInstitute of Animal Nutrition, Friedrich-Loeffler-Institute (FLI), Federal Research Institute for Animal Health, D-38116 Brunswick, Germany.
Julia LaurainOlmix, 56580 Brèhan, France.
Maria A RodriguezOlmix, 56580 Brèhan, France.
Francesc MolistSchothorst Feed Research, 8218 NA Lelystad, The Netherlands.ORCID 0000-0002-7915-3098
Sven DänickeInstitute of Animal Nutrition, Friedrich-Loeffler-Institute (FLI), Federal Research Institute for Animal Health, D-38116 Brunswick, Germany.ORCID 0000-0002-4913-4726
Regiane R SantosSchothorst Feed Research, 8218 NA Lelystad, The Netherlands.ORCID 0000-0001-7030-6097
Schothorst Feed Research · NLFriedrich-Loeffler-Institut · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sows were fed naturally contaminated diets containing: (i) 100 ppb zearalenone (ZEN) one week before farrowing and during the lactation period (at 26 days), (ii) 100 ppb ZEN one week before farrowing and 300 ppb ZEN during the lactation period, or (iii) 300 ppb ZEN one week before farrowing and during the lactation period. All diets contained 250 ppb deoxynivalenol (DON). The highest levels of ZEN, α-ZEL, or β-ZEL were observed in the serum of sows fed 300 ppb ZEN before farrowing and during lactation. However, only α-ZEL was significantly increased in the colostrum and milk of these sows. Sows fed the 300 ppb ZEN during the complete trial presented a significant decrease in backfat thickness before farrowing. This effect was accompanied by a decrease in serum leptin levels. These sows also presented a decrease in estradiol levels and this effect was observed in their piglets exposed during lactation, which presented increased glucagon-like peptide 1, but no changes in serum levels of ZEN, α-ZEL, or β-ZEL. Although all sows were fed the same levels of DON, the serum levels of DON and de-epoxy-DON were increased only in the serum of piglets from the sows fed a diet with the highest ZEN levels during the whole experimental period. Moreover, these piglets presented gut inflammation, as indicated by significantly increased calprotectin levels in their serum.

Indexed as

Animal FeedAnimalsDietDrug ResiduesFemaleFood ContaminationLactationMilkSwineTrichothecenesZearalenonedeoxynivalenolTrichothecenesZearalenonemetabolitesmilkpigletsserumsowszearalenone

Identifiers

PMID33419041
PMCPMC7825292
OpenAlexW3118830274

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.