Evidence map›Paper›PMID 33419035›Full record

ReviewMolecules (Basel, Switzerland)2021

Medicinal Properties and Bioactive Compounds from Wild Mushrooms Native to North America.

Mehreen Zeb, Chow H Lee

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Morphological and Phylogenetic Analyses Reveal Four New Species ofJournal of fungi (Basel, Switzerland) · 2026
    Article
  3. Bioactive Compounds and Antioxidant Activity ofMolecules (Basel, Switzerland) · 2025
    Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Activity of aurisin A isolated fromSaudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023
    Article
  10. Article
  11. Review
  12. Article
  13. Interpol Review of Drug Analysis 2019-2022.Forensic science international. Synergy · 2023
    Review
  14. Review
  15. Antiproliferative Fatty Acids Isolated from the Polypore FungusJournal of fungi (Basel, Switzerland) · 2022
    Article
  16. Molecules (Basel, Switzerland) · 2022
    Article
  17. Review
  18. The Effect of Edible Mushroom on Health and Their Biochemistry.International journal of microbiology · 2022
    Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Mehreen ZebChemistry and Biochemistry Program, University of Northern British Columbia, Prince George, BC V2N 4Z9, Canada.ORCID 0000-0003-0879-0468
Chow H LeeChemistry and Biochemistry Program, University of Northern British Columbia, Prince George, BC V2N 4Z9, Canada.

Funding

Canada Foundation for Innovation 34711Natural Sciences and Engineering Research Council of Canada 227158
6 · The paper itself

Abstract

Mushrooms, the fruiting bodies of fungi, are known for a long time in different cultures around the world to possess medicinal properties and are used to treat various human diseases. Mushrooms that are parts of traditional medicine in Asia had been extensively studied and this has led to identification of their bioactive ingredients. North America, while home to one of the world's largest and diverse ecological systems, has not subjected its natural resources especially its diverse array of mushroom species for bioprospecting purposes: Are mushrooms native to North America a good source for drug discovery? In this review, we compile all the published studies up to September 2020 on the bioprospecting of North American mushrooms. Out of the 79 species that have been investigated for medicinal properties, 48 species (60%) have bioactivities that have not been previously reported. For a mere 16 selected species, 17 new bioactive compounds (10 small molecules, six polysaccharides and one protein) have already been isolated. The results from our literature search suggest that mushrooms native to North America are indeed a good source for drug discovery.

Indexed as

Drug DiscoveryFungal PolysaccharidesFungal ProteinsAgaricalesHumansNorth AmericaFungal PolysaccharidesFungal Proteinsbioactive compoundsfungimedicinal mushroomsNorth Americawild mushrooms

Identifiers

PMID33419035
PMCPMC7825331

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.