Evidence map›Paper›PMID 33419016›Full record

ArticleBrain sciences2021

Effects of 6-Month Multimodal Physical Exercise Program on Bone Mineral Density, Fall Risk, Balance, and Gait in Patients with Alzheimer's Disease: A Controlled Clinical Trial.

A Silvia Puente-González, M Carmen Sánchez-Sánchez, Eduardo J Fernández-Rodríguez, J Elicio Hernández-Xumet, Fausto J Barbero-Iglesias, Roberto Méndez-Sánchez

Open access · goldAbstract read
In one paragraph

Article in Brain sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.

  1. A Meta-Analysis of Fall Risk in Older Adults With Alzheimer's Disease.Journal of the American Medical Directors Association · 2024
    Pooled it
  2. Pooled it
  3. Trial
  4. Review
  5. Article
  6. Review
  7. Gene Therapy for Skin Aging.Current gene therapy · 2025
    Review
  8. Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Disentangling Mitochondria in Alzheimer's Disease.International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

A Silvia Puente-GonzálezDepartment of Nursing and Physiotherapy, Universidad de Salamanca, 37007 Salamanca, Spain.
M Carmen Sánchez-SánchezDepartment of Nursing and Physiotherapy, Universidad de Salamanca, 37007 Salamanca, Spain.
Eduardo J Fernández-RodríguezDepartment of Nursing and Physiotherapy, Universidad de Salamanca, 37007 Salamanca, Spain.ORCID 0000-0002-2175-8545
J Elicio Hernández-XumetDepartment of Physical Medicine and Pharmacology, University of La Laguna, 38200 Santa Cruz de Tenerife, Spain.
Fausto J Barbero-IglesiasDepartment of Nursing and Physiotherapy, Universidad de Salamanca, 37007 Salamanca, Spain.ORCID 0000-0001-8407-4127
Roberto Méndez-SánchezDepartment of Nursing and Physiotherapy, Universidad de Salamanca, 37007 Salamanca, Spain.ORCID 0000-0002-4486-4076
Universidad de Salamanca · ESUniversidad de La Laguna · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We aimed to determine the short- and medium-term effects of a multimodal physical exercise program (MPEP) on bone health status, fall risk, balance, and gait in patients with Alzheimer's disease. A single-blinded, controlled clinical trial was performed where 72 subjects were allocated in a 3:1 ratio to an intervention group (IG;

Indexed as

Alzheimer’s diseasebalancebone densitycognitive impairmentfallsgaitmultimodal exercisemultitarget-directed interventionphysical exercisephysical function

Identifiers

PMID33419016
PMCPMC7825330
OpenAlexW3118418294

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.