Evidence map›Paper›PMID 33418898›Full record

ReviewInternational journal of molecular sciences2021

T6SS Mediated Stress Responses for Bacterial Environmental Survival and Host Adaptation.

Kai-Wei Yu, Peng Xue, Yang Fu, Liang Yang

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
9.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 59 citations in OpenAlex.

  1. Review
  2. Temperature-dependent reprogramming of virulence traits duringbioRxiv : the preprint server for biology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Comparative genomics of 'Microbial genomics · 2025
    Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. T6SS nuclease effectors inJournal of bacteriology · 2024
    Article
  16. Article
  17. Diverse Genotypes ofFoods (Basel, Switzerland) · 2024
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Kai-Wei YuSchool of Medicine, Southern University of Science and Technology, Shenzhen 518055, China.ORCID 0000-0001-7650-3278
Peng XueSchool of Medicine, Southern University of Science and Technology, Shenzhen 518055, China.ORCID 0000-0003-2755-7987
Yang FuSchool of Medicine, Southern University of Science and Technology, Shenzhen 518055, China.ORCID 0000-0002-5068-7248
Liang YangSchool of Medicine, Southern University of Science and Technology, Shenzhen 518055, China.
Southern University of Science and Technology · CN

Funding

Guangdong Natural Science Foundation for Distinguished Young Scholar 2020B1515020003
6 · The paper itself

Abstract

The bacterial type VI secretion system (T6SS) is a protein secretion apparatus widely distributed in Gram-negative bacterial species. Many bacterial pathogens employ T6SS to compete with the host and to coordinate the invasion process. The T6SS apparatus consists of a membrane complex and an inner tail tube-like structure that is surrounded by a contractile sheath and capped with a spike complex. A series of antibacterial or antieukaryotic effectors is delivered by the puncturing device consisting of a Hcp tube decorated by the VgrG/PAAR complex into the target following the contraction of the TssB/C sheath, which often leads to damage and death of the competitor and/or host cells. As a tool for protein secretion and interspecies interactions, T6SS can be triggered by many different mechanisms to respond to various physiological conditions. This review summarizes our current knowledge of T6SS in coordinating bacterial stress responses against the unfavorable environmental and host conditions.

Indexed as

Bacterial ProteinsGram-Negative BacteriaHost AdaptationHydrogen-Ion ConcentrationOxidative StressReactive Oxygen SpeciesSignal TransductionTemperatureType VI Secretion SystemsBacterial ProteinsReactive Oxygen SpeciesType VI Secretion Systemsbacteriasignaling interferencestress responseT6SS

Identifiers

PMID33418898
PMCPMC7825059
OpenAlexW3118393290

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.