ArticleClinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases2021
Gender disparities in coronavirus disease 2019 clinical trial leadership.
Article in Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Beyond Parity: Gender Inequities and Recommendations in Infectious Diseases and Clinical Microbiology Research.Infectious diseases & clinical microbiology · 2026Article
- Representation and career trajectories of female principal investigators in clinical trials, 2010-2023.Contemporary clinical trials communications · 2025Article
- Global perspectives to enhance strategies for advancing women in healthcare and STEMM leadership.Immunology and cell biology · 2025Review
- Representation of women on National Institutes of Health study sections before and during COVID-19 pandemic.Journal of clinical and translational science · 2025Article
- Inferring gender from first names: Comparing the accuracy of Genderize, Gender API, and the gender R package on authors of diverse nationality.PLOS digital health · 2024Article
- Trends in research approaches and gender in plant ecology dissertations over four decades.Ecology and evolution · 2024Review
- Gender Disparity in Leading Authorship of Critical Care Clinical Trials: A Systematic Review and Meta-Analysis.Cureus · 2024Review
- What Is the Performance of ChatGPT in Determining the Gender of Individuals Based on Their First and Last Names?JMIR AI · 2024Article
- Gender and racial differences in first and senior authorship of high-impact critical care randomized controlled trial studies from 2000 to 2022.Annals of intensive care · 2023Article
- US COVID-19 clinical trial leadership gender disparities.The Lancet. Digital health · 2023Article
- Gender Differences in National Institutes of Health Grant Submissions Before and During the COVID-19 Pandemic.Journal of women's health (2002) · 2022Article
- Article
- Determinants of COVID-19 Vaccinations among a State-Wide Year-Long Surveillance Initiative in a Conservative Southern State.Vaccines · 2022Article
- Gender profile of principal investigators in a large academic clinical trials group.Frontiers in surgery · 2022Article
- Gender Gap in Scientific Publications on COVID-19 in Italy During the First Wave of the Pandemic: An Observational Study.Frontiers in public health · 2022Observational
- Future developments in training.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2021Review
- Using genderize.io to infer the gender of first names: how to improve the accuracy of the inference.Journal of the Medical Library Association : JMLA · 2021Article
- The SARS-CoV-2 pandemic puts the spotlight on gender inequality in clinical research.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2021Article
- Performance of gender detection tools: a comparative study of name-to-gender inference services.Journal of the Medical Library Association : JMLA · 2021Article
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7 authors.
Funding
Abstract
objectivesTo compare the gender distribution of clinical trial leadership in coronavirus disease 2019 (COVID-19) clinical trials.
methodsWe searched https://clinicaltrials.gov/ and retrieved all clinical trials on COVID-19 from 1 January 2020 to 26 June 2020. As a comparator group, we have chosen two fields that are not related to emerging infections and infectious diseases: and considered not directly affected by the pandemic: breast cancer and type 2 diabetes mellitus (T2DM) and included studies within the aforementioned study period as well as those registered in the preceding year (pre-study period: 1 January 2019 to 31 December 2019). Gender of the investigator was predicted using the genderize.io application programming interface. The repository of the data sets used to collect and analyse the data are available at https://osf.io/k2r57/.
resultsOnly 27.8% (430/1548) of principal investigators among COVID-19-related studies were women, which is significantly different compared with 54.9% (156/284) and 42.1% (56/133) for breast cancer (p < 0.005) and T2DM (p < 0.005) trials over the same period, respectively. During the pre-study period, the proportion of principal investigators who were predicted to be women were 49.7% (245/493) and 44.4% (148/333) for breast cancer and T2DM trials, respectively, and the difference was not statistically significant when compared with results from the study period (p > 0.05).
conclusionWe demonstrate that less than one-third of COVID-19-related clinical trials are led by women, half the proportion observed in non-COVID-19 trials over the same period, which remained similar to the pre-study period. These gender disparities during the pandemic may not only indicate a lack of female leadership in international clinical trials and involvement in new projects but also reveal imbalances in women's access to research activities and funding during health emergencies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.