Evidence map›Paper›PMID 33417840›Full record

ArticleJournal of the American Medical Directors Association2021

Clinical Characteristics, Frailty, and Mortality of Residents With COVID-19 in Nursing Homes of a Region of Madrid.

Rafael Bielza, Juan Sanz, Francisco Zambrana, Estefanía Arias, Eduardo Malmierca, Laura Portillo, Israel J Thuissard, Ana Lung, Marta Neira, María Moral and 14 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of the American Medical Directors Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 4 pooled it
6.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 4 syntheses or guidelines pooled it, 82 citations in OpenAlex.

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  14. Analysis of Concentrated COVID-19 Outbreaks in Elderly Facilities in Suita City, Osaka Prefecture, Japan.International journal of environmental research and public health · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 2 institutions in 1 country.

Rafael BielzaDepartment of Geriatric Medicine, Hospital Universitario Infanta Sofía (San Sebastián de los Reyes), Madrid, Spain; Faculty of Biomedical and Health Sciences, Department of Medicine, Universidad Europea de Madrid, Madrid, Spain. Electronic address: rafael.bielza@salud.madrid.org.
Juan SanzDepartment of Dermatology, Hospital Universitario Infanta Sofía (San Sebastián de los Reyes), Madrid, Spain.
Francisco ZambranaFaculty of Biomedical and Health Sciences, Department of Medicine, Universidad Europea de Madrid, Madrid, Spain; Department of Oncology, Hospital Universitario Infanta Sofía (San Sebastián de los Reyes), Madrid, Spain.
Estefanía AriasDepartment of Geriatric Medicine, Hospital Universitario Infanta Sofía (San Sebastián de los Reyes), Madrid, Spain; Faculty of Biomedical and Health Sciences, Department of Medicine, Universidad Europea de Madrid, Madrid, Spain.
Eduardo MalmiercaFaculty of Biomedical and Health Sciences, Department of Medicine, Universidad Europea de Madrid, Madrid, Spain; Department of Internal Medicine, Hospital Universitario Infanta Sofía (San Sebastián de los Reyes), Madrid, Spain.
Laura PortilloFaculty of Biomedical and Health Sciences, Department of Medicine, Universidad Europea de Madrid, Madrid, Spain; Department of Pharmacy, Hospital Universitario Infanta Sofía (San Sebastián de los Reyes), Madrid, Spain.
Israel J ThuissardFaculty of Biomedical and Health Sciences, Department of Medicine, Universidad Europea de Madrid, Madrid, Spain.
Ana LungDepartment of Geriatric Medicine, Hospital Universitario Infanta Sofía (San Sebastián de los Reyes), Madrid, Spain; Faculty of Biomedical and Health Sciences, Department of Medicine, Universidad Europea de Madrid, Madrid, Spain.
Marta NeiraDepartment of Geriatric Medicine, Hospital Universitario Infanta Sofía (San Sebastián de los Reyes), Madrid, Spain; Faculty of Biomedical and Health Sciences, Department of Medicine, Universidad Europea de Madrid, Madrid, Spain.
María MoralDepartment of Palliative Care, Hospital Universitario Infanta Sofía (San Sebastián de los Reyes), Madrid, Spain.
Cristina Andreu-VázquezFaculty of Biomedical and Health Sciences, Department of Medicine, Universidad Europea de Madrid, Madrid, Spain.
Ana EstebanDepartment of Rheumatology, Hospital Universitario Infanta Sofía (San Sebastián de los Reyes), Madrid, Spain.
Marcela Irma RamírezDepartment of Endocrinology, Hospital Universitario Infanta Sofía (San Sebastián de los Reyes), Madrid, Spain.
Laura GonzálezDepartment of Neurology, Hospital Universitario Infanta Sofía (San Sebastián de los Reyes), Madrid, Spain.
Guillermo CarreteroDepartment of Orthopedics, Hospital Universitario Infanta Sofía (San Sebastián de los Reyes), Madrid, Spain.
Ricardo Vicente MorenoDepartment of Rehabilitation, Hospital Universitario Infanta Sofía (San Sebastián de los Reyes), Madrid, Spain.
Pilar MartínezDepartment of Rehabilitation, Hospital Universitario Infanta Sofía (San Sebastián de los Reyes), Madrid, Spain.
Javier LópezFaculty of Biomedical and Health Sciences, Department of Medicine, Universidad Europea de Madrid, Madrid, Spain; Department of Rehabilitation, Hospital Universitario Infanta Sofía (San Sebastián de los Reyes), Madrid, Spain.
Mar Esteban-OrtegaFaculty of Biomedical and Health Sciences, Department of Medicine, Universidad Europea de Madrid, Madrid, Spain; Department of Ophthalmology, Hospital Universitario Infanta Sofía (San Sebastián de los Reyes), Madrid, Spain.
Isabel GarcíaFaculty of Biomedical and Health Sciences, Department of Medicine, Universidad Europea de Madrid, Madrid, Spain; Department of Ophthalmology, Hospital Universitario Infanta Sofía (San Sebastián de los Reyes), Madrid, Spain.
María Antonia VaqueroFaculty of Biomedical and Health Sciences, Department of Medicine, Universidad Europea de Madrid, Madrid, Spain; Department of General Surgery, Hospital Universitario Infanta Sofía (San Sebastián de los Reyes), Madrid, Spain.
Ana LinaresFaculty of Biomedical and Health Sciences, Department of Medicine, Universidad Europea de Madrid, Madrid, Spain; Department of Urology, Hospital Universitario Infanta Sofía (San Sebastián de los Reyes), Madrid, Spain.
Ana Gómez-SantanaDepartment of Preventive Medicine, Hospital Universitario Infanta Sofía (San Sebastián de los Reyes), Madrid, Spain.
Jorge Gómez CerezoFaculty of Biomedical and Health Sciences, Department of Medicine, Universidad Europea de Madrid, Madrid, Spain; Department of Internal Medicine, Hospital Universitario Infanta Sofía (San Sebastián de los Reyes), Madrid, Spain.
Hospital Universitario Infanta Sofía · ESUniversidad Europea de Madrid · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo describe the clinical characteristics, 30-day mortality, and associated factors of patients living in nursing homes (NH) with COVID-19, from March 20 to June 1, 2020.

designThis is a retrospective study. A geriatric hospital-based team acted as a consultant and coordinated the care of older people living in NHs from the hospital. SETTING AND

participantsA total of 630 patients aged 70 and older with Coronavirus Disease 2019 COVID-19 living in 55 NHs.

methodsA logistic regression was performed to analyze the factors associated with mortality. In addition, Kaplan-Meier curves were applied according to mortality and its associated factors using the log-rank Mantel-Cox test.

resultsThe diagnosis of COVID-19 was mainly made by clinical compatibility (N = 430). Median age was 87 years, 64.6% were women and 45.9% were transferred to be cared for at the hospital. A total of 282 patients died (44.7%) within the 30 days of first attention by the team. A severe form of COVID-19 occurred in 473 patients, and the most frequent symptoms were dyspnea (n = 332) and altered level of consciousness (n = 301). According to multiple logistic regression, male sex (P = .019), the Clinical Frailty Score (CFS) ≥6 (P = .004), dementia (P = .012), dyspnea (P < .001), and having a severe form of COVID-19 (P = .001), were associated with mortality, whereas age and care setting were not. CONCLUSIONS AND IMPLICATIONS: Mortality of the residents living in NHs with COVID-19 was almost 45%. The altered level of consciousness as an atypical presentation of COVID-19 should be considered in this population. A severe form of the disease, present in more than three-quarters of patients, was associated with mortality, apart from the male sex, CFS ≥6, dementia, and dyspnea, whereas age and care setting were not. These findings may also help to recognize patients in which the Advance Care Planning process is especially urgent to assist in the decisions about their care.

Indexed as

Frail ElderlyNursing HomesAgedAged, 80 and overCOVID-19FemaleHumansKaplan-Meier EstimateMalePandemicsRetrospective StudiesSARS-CoV-2Spainclinical frailty scoregeriatric hospital-based teammortalityNursing homes

Identifiers

PMID33417840
PMCPMC7833075
OpenAlexW3112883832

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.