Evidence map›Paper›PMID 33417629›Full record

ReviewJournal of obstetrics and gynaecology of India2020

Post-caesarean Niche (Isthmocele) in Uterine Scar: An Update.

Vidushi Kulshrestha, Nutan Agarwal, Garima Kachhawa

Registry-linked trialOpen access · greenAbstract readReview
In one paragraph

Review in Journal of obstetrics and gynaecology of India, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06503627 (Incidence of Caesarean Scar Defect in Cases of Cesarean Section With and Without Bladder Flap Dissection), which is not on this map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06503627 phase2 / phase3completednot on this mapstarted 2022, after this paper: background citation

Incidence of Caesarean Scar Defect in Cases of Cesarean Section With and Without Bladder Flap Dissection

TypeinterventionalSponsorAlexandria UniversityRan2022 to 2024Enrolled250ConditionsCS Scar Defect(Niche) How to AvoidArmsbladder flap dissection
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 61 citations in OpenAlex.

  1. Pooled it
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  3. Is cesarean scar defect becoming history? The effect of uterotomy closure.Revista da Associacao Medica Brasileira (1992) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Vidushi KulshresthaDepartment of Obstetrics and Gynecology, All India Institute of Medical Sciences, 3082 A, 3rd Floor, Teaching Block, Ansari Nagar, New Delhi, 110029 India.ORCID 0000-0001-8519-6847
Nutan AgarwalDepartment of Obstetrics and Gynecology, All India Institute of Medical Sciences, 3082 A, 3rd Floor, Teaching Block, Ansari Nagar, New Delhi, 110029 India.
Garima KachhawaDepartment of Obstetrics and Gynecology, All India Institute of Medical Sciences, 3082 A, 3rd Floor, Teaching Block, Ansari Nagar, New Delhi, 110029 India.
All India Institute of Medical Sciences · INArtemis Hospitals · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Uterine niche is one of the emerging complications of caesarean section. With rising caesarean rates, the caesarean-related iatrogenic complications are also on the rise. These include placenta accreta, scar ectopic pregnancy and uterine niche which is a newer entity being described in the recent literature. Uterine niche, also described as uterine isthmocele, caesarean scar defect and diverticulum, is an iatrogenic defect in the myometrium at the site of previous caesarean scar due to defective tissue healing. Patients may have varied symptoms including abnormal uterine bleeding, post-menstrual spotting and infertility, though many women may be asymptomatic and diagnosed incidentally. Diagnosis is made radiologically by transvaginal sonography, saline instillation sonohysterography or magnetic resonance imaging. Occurrence of niche may be prevented by using correct surgical technique during caesarean. Patients may be managed medically; however, subfertility and persistent symptoms may require surgical correction either by hysteroscopic resection or transabdominal or transvaginal repair. This mini-review comprehensively covers the potential risk factors, clinical presentation, diagnosis and management of this increasingly encountered condition due to rising caesarean rates.

Indexed as

Caesarean scar defectIsthmoceleUterine niche

Identifiers

PMID33417629
PMCPMC7758379
OpenAlexW3088438824

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.