Evidence map›Paper›PMID 33417138›Full record

ArticleJournal of autism and developmental disorders2021

Toward Novel Tools for Autism Identification: Fusing Computational and Clinical Expertise.

Laura L Corona, Liliana Wagner, Joshua Wade, Amy S Weitlauf, Jeffrey Hine, Amy Nicholson, Caitlin Stone, Alison Vehorn, Zachary Warren

Abstract read
In one paragraph

Article in Journal of autism and developmental disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Measuring Developmental Delays: Comparison of Parent Report and Direct Testing.Journal of autism and developmental disorders · 2025
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  12. Reliability of the Commonly Used and Newly-Developed Autism Measures.Journal of autism and developmental disorders · 2024
    Article
  13. Article
  14. Paisley: Preliminary validation of a novel app-based e-Screener for ASD in children 18-36 months.Autism research : official journal of the International Society for Autism Research · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Laura L CoronaVanderbilt Kennedy Center/Treatment and Research Institute for Autism Spectrum Disorders, Vanderbilt University Medical Center, Nashville, TN, USA. Laura.L.Corona@vumc.org.ORCID http://orcid.org/0000-0001-8166-253X
Liliana WagnerVanderbilt Kennedy Center/Treatment and Research Institute for Autism Spectrum Disorders, Vanderbilt University Medical Center, Nashville, TN, USA.
Joshua WadeAdaptive Technology Consulting, LLC, Nashville, TN, USA.
Amy S WeitlaufVanderbilt Kennedy Center/Treatment and Research Institute for Autism Spectrum Disorders, Vanderbilt University Medical Center, Nashville, TN, USA.
Jeffrey HineVanderbilt Kennedy Center/Treatment and Research Institute for Autism Spectrum Disorders, Vanderbilt University Medical Center, Nashville, TN, USA.
Amy NicholsonVanderbilt Kennedy Center/Treatment and Research Institute for Autism Spectrum Disorders, Vanderbilt University Medical Center, Nashville, TN, USA.
Caitlin StoneVanderbilt Kennedy Center/Treatment and Research Institute for Autism Spectrum Disorders, Vanderbilt University Medical Center, Nashville, TN, USA.
Alison VehornVanderbilt Kennedy Center/Treatment and Research Institute for Autism Spectrum Disorders, Vanderbilt University Medical Center, Nashville, TN, USA.
Zachary WarrenVanderbilt Kennedy Center/Treatment and Research Institute for Autism Spectrum Disorders, Vanderbilt University Medical Center, Nashville, TN, USA.

Funding

Vanderbilt Institute for Clinical and Translational Research (VICTR) -Identifying correlates of functional immunity in SARS-CoV-2 convalescent plasmaUL1TR002243 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Paul A. Harris, Wesley H Self · 2017 to 2026
$130.7M
Overall: Eunice Kennedy Shriver Intellectual and Developmental Disabilities Research Center at VanderbiltP50HD103537 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Lea K Davis · 2020 to 2026
$10.3M
Autoscreen: An innovative e-health solution for early identification of Autism Spectrum Disorder Phase IIR44MH115528 · NIMH · ADAPTIVE TECHNOLOGY CONSULTING, LLC · PI WADE, JOSHUA W · 2019 to 2020
$1.0M
Can novel telemedicine tools reduce disparities related to early identification of autismR21MH118539 · NIMH · VANDERBILT UNIVERSITY MEDICAL CENTER · PI WARREN, ZACHARY E · 2019 to 2020
$435k
Center for Clinical and Translational Sciences, University of Texas Health Science Center at Houston (US) 5UL1TR002243-03Eunice Kennedy Shriver National Institute of Child Health and Human Development U54 HD08321National Institutes of Health (US) R43MH115528National Institutes of Health (US) R44MH115528NCATS NIH HHS UL1 TR002243NIH/NIMH R21MH118539NIMH NIH HHS R21 MH118539NIMH NIH HHS R44 MH115528
6 · The paper itself

Abstract

Barriers to identifying autism spectrum disorder (ASD) in young children in a timely manner have led to calls for novel screening and assessment strategies. Combining computational methods with clinical expertise presents an opportunity for identifying patterns within large clinical datasets that can inform new assessment paradigms. The present study describes an analytic approach used to identify key features predictive of ASD in young children, drawn from large amounts of data from comprehensive diagnostic evaluations. A team of expert clinicians used these predictive features to design a set of assessment activities allowing for observation of these core behaviors. The resulting brief assessment underlies several novel approaches to the identification of ASD that are the focus of ongoing research.

Indexed as

Autism Spectrum DisorderAutistic DisorderChildChild, PreschoolHumansMass ScreeningOutcome Assessment, Health CareAssessmentAutism spectrum disorderMachine learningYoung children

Identifiers

PMID33417138
PMCPMC7791904

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.