Evidence map›Paper›PMID 33417095›Full record

ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2021

Microbial spectrum and antibiotic sensitivity in infantile dacryocystitis.

Huiling Qing, Zhengwei Yang, Menghai Shi, Junge Zhang, Shengtao Sun, Lei Han

Abstract read
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In one paragraph

Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Huiling Qing *Department of Ophthalmology, Henan Eye Hospital, Henan Eye Institute, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, NO.7, Wei-wu Road, Zhengzhou, 450003, China. qinghuiling@sina.com.ORCID http://orcid.org/0000-0001-6440-3181
Zhengwei Yang *Department of Ophthalmology, Henan Eye Hospital, Henan Eye Institute, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, NO.7, Wei-wu Road, Zhengzhou, 450003, China.
Menghai ShiDepartment of Ophthalmology, Henan Eye Hospital, Henan Eye Institute, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, NO.7, Wei-wu Road, Zhengzhou, 450003, China.
Junge ZhangDepartment of Ophthalmology, Henan Eye Hospital, Henan Eye Institute, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, NO.7, Wei-wu Road, Zhengzhou, 450003, China.
Shengtao SunDepartment of Ophthalmology, Henan Eye Hospital, Henan Eye Institute, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, NO.7, Wei-wu Road, Zhengzhou, 450003, China.
Lei HanDepartment of Ophthalmology, Henan Eye Hospital, Henan Eye Institute, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, NO.7, Wei-wu Road, Zhengzhou, 450003, China.
Zhengzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo identify the characteristics and the spectrum of microbial agents of infantile dacryocystitis and to assess the trends in both antibiotic sensitivities and pathogens over the past 10 years.

methodsThe microbial and medical records of 546 culture-proven patients (546 eyes) of infantile dacryocystitis diagnosed at Henan Eye Hospital between January 2009 and December 2018 were retrospectively reviewed. Patient demographics, microbial analysis, and susceptibility rates to various antibiotics were done. A chi-squared test for trends was applied to evaluate changes in antibiotic susceptibility and microbial spectrum over time.

resultsA total of 546 patients with infantile dacryocystitis were documented. The average age was 2.97 ± 4.15 months, and 42.7% were female. The proportion of gram-positive microbes, gram-negative microbes, and fungi was 80.2, 19.4, and 0.4%, respectively. Minocycline was sensitive to gram-positive bacteria (98.0%). Imipenem was sensitive to gram-negative bacteria (89.2%). Increasing susceptibility was observed in two bacterial isolates: Staphylococcus aureus (P = 0.005) and Streptococcus mitis (P = 0.001). Decreasing susceptibility was observed in one bacterial isolate: Staphylococcus epidermidis (P < 0.0001). Increasing microbial susceptibility over time was detected for 12 antibiotics. Decreasing microbial sensitivity was observed for one antibiotic.

conclusionsThe most common cause of infantile dacryocystitis is Staphylococcus epidermidis. Though a significant trend towards increasing microbial sensitivity to some antibiotics was observed, including glycopeptides, cephalosporins, fluoroquinolones, tetracyclines, and lincosamides, a significant trend towards decreasing microbial sensitivity to amikacin was also detected.

Indexed as

Anti-Bacterial AgentsDacryocystitisChild, PreschoolDrug Resistance, BacterialFemaleGram-Negative BacteriaHumansMicrobial Sensitivity TestsRetrospective StudiesAnti-Bacterial AgentsAntibiotic sensitivityInfantile dacryocystitisMicrobial sensitivityMicrobial spectrum

Identifiers

PMID33417095
OpenAlexW3118811601

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.