Evidence map›Paper›PMID 33417005›Full record

ArticleJournal of neurology2021

Head tremor and pain in cervical dystonia.

Jeanne P Vu, Ha Yeon Lee, Qiyu Chen, Elizabeth Cisneros, Richard L Barbano, Christopher G Goetz, Joseph Jankovic, Hyder A Jinnah, Joel S Perlmutter, Brian D Berman and 4 more

Abstract read
In one paragraph

Article in Journal of neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Trial
  2. Trial
  3. An Exploratory, Randomized, Double-Blind Clinical Trial of Dipraglurant for Blepharospasm.Movement disorders : official journal of the Movement Disorder Society · 2024
    Trial
  4. Trial
  5. Observational
  6. Article
  7. Factors influencing botulinum toxin response in cervical dystonia: a two-center GAS-based study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Observational
  8. Article
  9. Article
  10. Article
  11. Article
  12. [Pain and cervical dystonia].Schmerz (Berlin, Germany) · 2024
    Review
  13. Clinical characteristics of patients with migraine accompanied by tremor.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2024
    Article
  14. Article
  15. Hold that pose: capturing cervical dystonia's head deviation severity from video.Annals of clinical and translational neurology · 2022
    Article
  16. Article
  17. Tourette Syndrome and Driving.Movement disorders clinical practice · 2021
    Article
  18. Tremor Syndromes: An Updated Review.Frontiers in neurology · 2021
    Review
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Jeanne P VuInstitute for Neural Computation, University of California, La Jolla, San Diego, CA, USA.ORCID http://orcid.org/0000-0003-2665-2763
Ha Yeon LeeInstitute for Neural Computation, University of California, La Jolla, San Diego, CA, USA.
Qiyu ChenInstitute for Neural Computation, University of California, La Jolla, San Diego, CA, USA.
Elizabeth CisnerosInstitute for Neural Computation, University of California, La Jolla, San Diego, CA, USA.
Richard L BarbanoDepartment of Neurology, University of Rochester, Rochester, NY, USA.
Christopher G GoetzDepartment of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA.
Joseph JankovicDepartment of Neurology, Parkinson's Disease Center and Movement Disorders Clinic, Baylor College of Medicine, Houston, TX, USA.
Hyder A JinnahDepartments of Neurology and Human Genetics, Emory University, Atlanta, GA, USA.
Joel S PerlmutterDepartment of Neurology, Washington University School of Medicine, St. Louis, MO, USA.
Brian D BermanDepartment of Neurology, Virginia Commonwealth University, Richmond, VA, USA.
Mark I AppelbaumDepartment of Psychology, University of California, La Jolla, San Diego, CA, USA.
Glenn T StebbinsDepartment of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA.
Cynthia L ComellaDepartment of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA.
David A PetersonInstitute for Neural Computation, University of California, La Jolla, San Diego, CA, USA. dap@salk.edu.

Funding

Dystonia Coalition- Pilot ProjectU54NS116025 · NINDS · EMORY UNIVERSITY · PI JINNAH, HYDER A · 2019 to 2023
$7.1M
Dystonia CoalitionU54NS065701 · NINDS · EMORY UNIVERSITY · PI JINNAH, HYDER A · 2009 to 2014
$7.0M
Dystonia CoalitionU54TR001456 · NCATS · EMORY UNIVERSITY · PI JINNAH, HYDER A · 2015 to 2016
$2.5M
NCATS NIH HHS U54 TR001456NINDS NIH HHS U54 NS065701NINDS NIH HHS U54 NS116025Office of the Under Secretary of Defense W81XWH-17-1-0393
6 · The paper itself

Abstract

backgroundAlthough head tremor (HT) and pain are prevalent in cervical dystonia (CD), their joint relationship to phenotypic features of focal dystonia remains unclear.

objectivesWe examined how severity of HT and pain are associated with age of CD onset and duration, and whether HT subtypes ("jerky" or "regular") exhibit distinct relationships between severity of HT and pain.

methodsThe severity of HT and pain were assessed with the Toronto Western Spasmodic Torticollis Rating Scale in retrospective review of 188 CD patients recruited through the Dystonia Coalition.

resultsHT severity was associated with longer CD duration (p < 0.0005), whereas pain severity was associated with younger age at onset (p = 0.043). HT severity and pain severity were not correlated for jerky HT (p = 0.996), but positively correlated for regular HT (p = 0.01).

conclusionsThe distinct associations of HT and pain with age at onset, disease duration, and HT subtype further characterize the heterogeneity of CD's clinical presentation and suggest similarly heterogeneous underlying mechanisms.

Indexed as

TorticollisHumansPainRetrospective StudiesTremorCervical dystoniaDystonic tremorHead tremorPain

Identifiers

PMID33417005
PMCPMC8076053

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.