Evidence map›Paper›PMID 33416975›Full record

ArticleEuropean radiology2021

Soft tissue sarcomas: IVIM and DKI correlate with the expression of HIF-1α on direct comparison of MRI and pathological slices.

Xiangwen Li, Lin Yang, Qimeng Wang, Juan Tao, Ziang Pan, Shaowu Wang

Abstract read
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In one paragraph

Article in European radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. DKI andBMC medical imaging · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Neon ion (Cancer science · 2024
    Article
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  13. Article
  14. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Xiangwen Li *Department of Radiology, The Second Hospital, Dalian Medical University, Dalian, Liaoning Province, China.
Lin Yang *Department of Radiology, The Second Hospital, Dalian Medical University, Dalian, Liaoning Province, China.
Qimeng WangDepartment of Pathology, The Second Hospital, Dalian Medical University, Dalian, China.
Juan TaoDepartment of Pathology, The Second Hospital, Dalian Medical University, Dalian, China.
Ziang PanDepartment of Pathology, The Second Hospital, Dalian Medical University, Dalian, China.
Shaowu WangDepartment of Radiology, The Second Hospital, Dalian Medical University, Dalian, Liaoning Province, China. wsw_2018@163.com.ORCID http://orcid.org/0000-0002-2221-1154
Dalian Medical University · CN

Funding

National Natural Science Foundation of China 81771804
6 · The paper itself

Abstract

objectiveTo investigate the correlation of intravoxel incoherent motion (IVIM) and diffusion kurtosis imaging (DKI) parameters with the expression of HIF-1α in soft tissue sarcoma (STS).

methodsThis prospective study was approved by the institutional ethics committee. Written informed consent was obtained from all patients. Forty patients with STS who underwent 3.0 T MRI, including IVIM and DKI, were included in the study. Standard apparent diffusion coefficient (ADC), true ADC (D

resultsD

conclusionsThis preliminary study demonstrated the association of IVIM and DKI parameters with the expression of HIF-1α in STS. KEY POINTS: • IVIM and DKI parameters are correlated with the expression of HIF-1α in STS. • The MRI-pathology control method can be used in clinical studies to ensure correspondence between MRI slices and pathology sections.

Indexed as

Diffusion Tensor ImagingSarcomaDiffusion Magnetic Resonance ImagingHumansMagnetic Resonance ImagingMotionProspective StudiesSensitivity and SpecificityDiffusion magnetic resonance imagingHypoxia-inducible factor 1Sarcoma

Identifiers

PMID33416975
OpenAlexW3119551184

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.