Evidence map›Paper›PMID 33416206›Full record

ArticleHuman brain mapping2021

Discriminating subcortical ischemic vascular disease and Alzheimer's disease by diffusion kurtosis imaging in segregated thalamic regions.

Min-Chien Tu, Sheng-Min Huang, Yen-Hsuan Hsu, Jir-Jei Yang, Chien-Yuan Lin, Li-Wei Kuo

Abstract read
In one paragraph

Article in Human brain mapping, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Min-Chien TuDepartment of Neurology, Taichung Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Taichung, Taiwan.ORCID 0000-0002-8883-1313
Sheng-Min HuangInstitute of Biomedical Engineering and Nanomedicine, National Health Research Institutes, Miaoli, Taiwan.ORCID 0000-0003-2930-8562
Yen-Hsuan HsuDepartment of Psychology, National Chung Cheng University, Chiayi, Taiwan.
Jir-Jei YangDepartment of Radiology, Taichung Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Taichung, Taiwan.
Chien-Yuan LinGE Healthcare, Taipei, Taiwan.
Li-Wei KuoInstitute of Biomedical Engineering and Nanomedicine, National Health Research Institutes, Miaoli, Taiwan.ORCID 0000-0002-0306-7329

Funding

Department of Health NHRI-BN-109-PP-06Department of Health NHRI-BN-109-SP-11Department of Health NHRI-EX109-10903NI
6 · The paper itself

Abstract

Differentiating between subcortical ischemic vascular disease (SIVD), Alzheimer's disease (AD), and normal cognition (NC) remains a challenge, and reliable neuroimaging biomarkers are needed. The current study, therefore, investigated the discriminative ability of diffusion kurtosis imaging (DKI) metrics in segregated thalamic regions and compare with diffusion tensor imaging (DTI) metrics. Twenty-three SIVD patients, 30 AD patients, and 24 NC participants underwent brain magnetic resonance imaging. The DKI metrics including mean kurtosis (MK), axial kurtosis (K

Indexed as

AgedAged, 80 and overAlzheimer DiseaseBrain IschemiaDiagnosis, DifferentialDiffusion Magnetic Resonance ImagingDiffusion Tensor ImagingFemaleFrontal LobeHumansMaleNerve NetThalamusAlzheimer's diseasecanonical discriminant analysisdementiadiffusion kurtosis imagingdiffusion tensor imagingsubcortical ischemic vascular diseasethalamus

Identifiers

PMID33416206
PMCPMC8046043

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.