Evidence map›Paper›PMID 33415757›Full record

ArticleAnnals of the New York Academy of Sciences2021

Assessment of salt intake to consider salt as a fortification vehicle for thiamine in Cambodia.

Kathleen Chan, Jelisa Gallant, Shalem Leemaqz, Dare A Baldwin, Mam Borath, Hou Kroeun, Jeffrey R Measelle, Rem Ngik, Sophonneary Prak, Frank T Wieringa and 3 more

Abstract read
In one paragraph

Article in Annals of the New York Academy of Sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Kathleen ChanDepartment of Applied Human Nutrition, Mount Saint Vincent University, Halifax, Nova Scotia, Canada.
Jelisa GallantDepartment of Applied Human Nutrition, Mount Saint Vincent University, Halifax, Nova Scotia, Canada.
Shalem LeemaqzWomen and Kids Theme, South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia.
Dare A BaldwinDepartment of Psychology, University of Oregon, Eugene, Oregon.
Mam BorathNational Sub-Committee for Food Fortification, Cambodia Ministry of Planning, Phnom Penh, Cambodia.
Hou KroeunCambodia Country Office, Helen Keller International, Cambodia, Phnom Penh, Cambodia.
Jeffrey R MeaselleDepartment of Psychology, University of Oregon, Eugene, Oregon.
Rem NgikCambodia Country Office, Helen Keller International, Cambodia, Phnom Penh, Cambodia.
Sophonneary PrakNational Nutrition Programme, Cambodia Ministry of Health, Phnom Penh, Cambodia.
Frank T WieringaUMR-204 NutriPass, Institut de recherche pour le développement, Montpellier, France.ORCID 0000-0002-6010-355X
Lisa N YellandWomen and Kids Theme, South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia.
Tim J GreenWomen and Kids Theme, South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia.ORCID 0000-0002-0667-4300
Kyly C WhitfieldDepartment of Applied Human Nutrition, Mount Saint Vincent University, Halifax, Nova Scotia, Canada.ORCID 0000-0001-8315-8927

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thiamine deficiency is a public health issue in Cambodia. Thiamine fortification of salt has been proposed; however, the salt intake of lactating women, the target population, is currently unknown. We estimated salt intakes among lactating women (<6 months postpartum) using three methods: repeat observed-weighed intake records and 24-h urinary sodium excretions (n = 104), and household salt disappearance (n = 331). Usual salt intake was estimated by adjusting for intraindividual intakes using the National Cancer Institute method, and a thiamine salt fortification scenario was modeled using a modified estimated average requirement (EAR) cut-point method. Unadjusted salt intake from observed intakes was 9.3 (8.3-10.3) g/day, which was not different from estimated salt intake from urinary sodium excretions, 9.0 (8.4-9.7) g/day (P = 0.3). Estimated salt use from household salt disappearance was 11.3 (10.7-11.9) g/person/day. Usual (adjusted) salt intake from all sources was 7.7 (7.4-8.0) g/day. Assuming no stability losses, a modeled fortification dose of 275 mg thiamine/kg salt could increase thiamine intakes from fortified salt to 2.1 (2.0-2.2) mg/day, with even low salt consumers reaching the EAR of 1.2 mg/day from fortified salt alone. These findings, in conjunction with future sensory and stability research, can inform a potential salt fortification program in Cambodia.

Indexed as

Dietary SupplementsFood, FortifiedAdultCambodiaDisease ManagementDisease SusceptibilityFamily CharacteristicsFemaleHumansMalePregnancyPublic Health SurveillanceSociodemographic FactorsSodium Chloride, DietaryThiamineThiamine DeficiencySodium Chloride, DietaryThiamineberiberifortificationhuman milksaltthiamineurinary sodium

Identifiers

PMID33415757
PMCPMC8451827

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.