Evidence map›Paper›PMID 33415698›Full record

ArticleMedical & biological engineering & computing2021

Smoothed particle hydrodynamics simulation of biphasic soft tissue and its medical applications.

Yi-Jui Chang, Peyman Benharash, Erik P Dutson, Jeff D Eldredge

Abstract read
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In one paragraph

Article in Medical & biological engineering & computing, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yi-Jui ChangMechanical and Aerospace Engineering Department, University of California, Los Angeles, CA, USA.ORCID http://orcid.org/0000-0001-7750-8767
Peyman BenharashDepartment of Surgery, University of California, Los Angeles, CA, USA.
Erik P DutsonDepartment of Surgery, University of California, Los Angeles, CA, USA.
Jeff D EldredgeMechanical and Aerospace Engineering Department, University of California, Los Angeles, CA, USA. jdeldre@g.ucla.edu.

Funding

U.S. Army Medical Research Acquisition Activity W81XWH-15-1-0147U.S. Office of Naval Research N00014-13-C-0357
6 · The paper itself

Abstract

Modeling the coupled fluid and elastic mechanics of blood perfused soft tissues is important for medical applications. In particular, the current study aims to capture the effect of tissue swelling and the transport of blood through damaged tissue under bleeding or hemorrhaging conditions. The soft tissue is considered a dynamic poro-hyperelastic material with blood-filled voids. A biphasic formulation-effectively, a generalization of Darcy's law-is utilized, treating the phases as occupying fractions of the same volume. A Stokes-like friction force and a pressure that penalizes deviations from volume fractions summing to unity serve as the interaction force between solid and liquid phases. The resulting equations for both phases are discretized with the method of smoothed particle hydrodynamics (SPH). The solver is validated separately on each phase and demonstrates good agreement with exact solutions in test problems. Simulations of oozing, hysteresis, swelling, drying and shrinkage, and tissue fracturing and hemorrhage are shown in the paper. Graphical Abstract In the paper, a new methodology for the numerical simulation of the full dynamic response of blood-perfused soft tissues was developed.

Indexed as

HydrodynamicsComputer SimulationHyperelasticityMultiphasesSmoothed particle hydrodynamicsSoft tissueTheory of porous media

Identifiers

PMID33415698

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.