Evidence map›Paper›PMID 33415677›Full record

ArticleMolecular imaging and biology2021

Impact of PET/MRI in the Treatment of Pancreatic Adenocarcinoma: a Retrospective Cohort Study.

Felipe S Furtado, Cristina R Ferrone, Susanna I Lee, Mark Vangel, David A Rosman, Colin Weekes, Motaz Qadan, Carlos Fernandez-Del Castillo, David P Ryan, Lawrence S Blaszkowsky and 7 more

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in Molecular imaging and biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06265272 (Technical Development and Clinical Validation of a Comprehensive One-stop Shop Assessment of the Cirrhotic Liver With [68Ga]Ga-PSMA-11 PET/MRI), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.1field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06265272 recruitingnot on this mapstarted 2023, after this paper: background citation

Technical Development and Clinical Validation of a Comprehensive One-stop Shop Assessment of the Cirrhotic Liver With [68Ga]Ga-PSMA-11 PET/MRI

TypeobservationalSponsorMassachusetts General HospitalRan2023 to 2026Enrolled45ConditionsLiver Cirrhosis, Hepatic Cell Carcinoma, Portal HypertensionArmsInjection of a gadolinium contrast agen, Radiotracer Injection, Imaging
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Post-neoadjuvant treatment pancreatic cancer resectability and outcome prediction using CT,Cancer imaging : the official publication of the International Cancer Imaging Society · 2023
    Article
  3. Article
  4. The value ofQuantitative imaging in medicine and surgery · 2023
    Article
  5. Review
  6. Comments onChinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2022
    Article
  7. Observational
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 5 institutions in 5 countries.

Felipe S FurtadoDepartment of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02114, USA.
Cristina R FerroneDepartment of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02114, USA.
Susanna I LeeDepartment of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02114, USA.
Mark VangelDepartment of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02114, USA.
David A RosmanDepartment of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02114, USA.
Colin WeekesCancer Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Motaz QadanDepartment of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02114, USA.
Carlos Fernandez-Del CastilloDepartment of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02114, USA.
David P RyanCancer Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Lawrence S BlaszkowskyCancer Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Theodore S HongDepartment of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02114, USA.
Jeffrey W ClarkCancer Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Robin StriarDepartment of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02114, USA.
David GrosharDepartment of Nuclear Medicine, Assuta Medical Centers, Tel Aviv, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Lina G CañamaqueHospital Universitario Madrid Sanchinarro, Madrid, Spain.
Lale UmutluDepartment of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, Essen, Germany.
Onofrio A CatalanoDepartment of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02114, USA. ocatalano@mgh.harvard.edu.ORCID 0000-0001-7733-4138
Harvard University · USEssen University Hospital · DEHospital Universitario HM Sanchinarro · ESParthenope University of Naples · ITTel Aviv University · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeImaging is central to the diagnosis and management of Pancreatic Ductal Adenocarcinoma (PDAC). This study evaluated if positron emission tomography (PET)/magnetic resonance imaging (MRI) elicited treatment modifications in PDAC when compared to standard of care imaging (SCI). PROCEDURES: This retrospective study included consecutive patients with PDAC who underwent 2-deoxy-2-[

resultsTwenty-five patients underwent 37 PET/MRI's, mean age was 65 ± 9 years and 13 (13/25, 52 %) were men. 49 % (18/37, 95 % CI 33-64 %) of the PET/MRI scans changed clinical management. Whether the SCI included a PET/CT or not did not significantly modify the probability of management change (OR = 0.9, 95 % CI 0.2-4, p = 1). One hundred percent (33/33) of the available follow-up data confirmed PET/MRI findings.

conclusionsPET/MRI significantly changed PDAC management, consistently across the different SCI modalities it was compared to. These findings suggest a role for PET/MRI in the management of PDAC.

Indexed as

AdenocarcinomaAgedFemaleFluorodeoxyglucose F18HumansMagnetic Resonance ImagingMaleMiddle AgedMultimodal ImagingPancreatic NeoplasmsPositron-Emission TomographyPositron Emission Tomography Computed TomographyRetrospective StudiesTomography, X-Ray ComputedFluorodeoxyglucose F18FDGManagement changesMRIPancreatic cancerPETPET/MRI

Identifiers

PMID33415677
OpenAlexW3119670643

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.