ArticleNeurosurgical review2021
Postoperative stroke and neurological outcomes in the early phase after revascularization surgeries for moyamoya disease: an age-stratified comparative analysis.
Article in Neurosurgical review, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- Postoperative seizure, stroke, hemorrhage, and cerebral hyperperfusion syndrome rates in adult patients with moyamoya disease undergoing revascularization: a systematic review and proportional meta-analysis.Neurosurgical review · 2026Pooled it
- Patient perspective on large-language model responses to questions about Moyamoya.Acta neurochirurgica · 2026Article
- Intraoperative application of FFR pressure wire and FLOW800 imaging as predictors of postoperative cerebral perfusion abnormalities in Moyamoya disease.Frontiers in surgery · 2026Article
- Introducing an index on prediction of post-revascularization cerebral infarction using preoperative CT perfusion parameters in moyamoya disease.Insights into imaging · 2025Article
- Assessment of donor-vessel after STA-MCA bypass for moyamoya disease using handheld Doppler to confirm bypass patency and predict perioperative hyperperfusion.World neurosurgery: X · 2024Article
- Individualised evaluation based on pathophysiology for moyamoya vasculopathy: application in surgical revascularisation.Stroke and vascular neurology · 2024Article
- Pediatric Moyamoya Revascularization Perioperative Care: A Modified Delphi Study.Neurocritical care · 2024Article
- Usefulness of combined bypass surgery for moyamoya disease in infants under 1 year of age: A technical case report.Surgical neurology international · 2024Article
- Perioperative Management of Pediatric Patients with Moyamoya Arteriopathy.Journal of pediatric intensive care · 2023Review
- Effects of superficial temporal artery to middle cerebral artery bypass on postoperative infarction rates among young children (≤ 5 years old) with moyamoya disease.Neurosurgical review · 2023Article
- [Three-dimensional pseudo-continuous arterial spin labeling for evaluation of cerebral hemodynamic changes after revascularization in adult patients with moyamoya disease].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2023Article
- European Stroke Organisation (ESO) Guidelines on Moyamoya angiopathy Endorsed by Vascular European Reference Network (VASCERN).European stroke journal · 2023Article
- Angioarchitectural Factors Associated with Postoperative Cerebral Infarction in Ischemic Moyamoya Disease.Brain sciences · 2022Article
- Changes in cerebral blood flow in the postoperative chronic phase after combined cerebral revascularization for moyamoya disease with ischaemic onset.Neurosurgical review · 2022Article
- Challenging direct bypass surgery for very young children with moyamoya disease: technical notes.Neurosurgical review · 2022Article
- Spatially separate cerebral infarction in the posterior cerebral artery territory after combined revascularization of the middle cerebral artery territory in an adult patient with moyamoya disease and fetal-type posterior communicating artery: illustrative case.Journal of neurosurgery. Case lessons · 2022Article
- Paradoxical symptomatic cerebral blood flow decreases after combined revascularization surgery for patients with pediatric moyamoya disease: illustrative case.Journal of neurosurgery. Case lessons · 2022Article
- Indirect revascularization vs. non-surgical treatment for Moyamoya disease and Moyamoya syndrome: A comparative effectiveness study.Frontiers in neurology · 2022Article
- Postoperative cerebral infarction after revascularization in patients with moyamoya disease: Incidence and risk factors.Frontiers in neurology · 2022Article
- The preoperative focal cerebral blood flow status may be associated with slow flow in the bypass graft after combined surgery for moyamoya disease.Surgical neurology international · 2022Article
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Authors and funding
16 authors at 2 institutions in 1 country.
Funding
Abstract
Stroke and neurological outcomes in the early phase following revascularization for moyamoya disease (MMD) may depend on the patient's age. In this study, an age-stratified comparative analysis was performed to clarify this issue. We reviewed 105 MMD patients who underwent 179 revascularization surgeries. The demographic characteristics were collected in four age groups (≤ 5 and 6-17 years for pediatric patients and 18-49 and ≥ 50 years for adults). Additionally, we assessed the incidence of subsequent stroke and deterioration of modified Rankin Scale (mRS) score. Then, we evaluated predictors of postoperative stroke and mRS deterioration using logistic regression. The mean patient age was 26.2 ± 18.5 years. No significant difference in the incidence of postoperative stroke was observed between age groups; however, the incidence tended to be increased among patients aged ≤ 5 years (17.9%) and patients aged ≥ 50 years (16.7%). Deterioration of mRS scores was significantly associated with ages ≤ 5 years (17.9%) and ≥ 50 years (11.1%). Logistic regression showed that posterior cerebral artery involvement (odds ratio [OR], 4.6) and postoperative transient neurological events (TNEs) (OR, 5.93) were risk factors for postoperative stroke. Age ≤ 5 years (OR, 9.73), postoperative TNEs (OR, 7.38), and postoperative stroke (OR, 49) were identified as predictors of unfavorable neurological outcomes. The novel feature of this comparative analysis by age group is that membership in the early-childhood MMD patient group (under 5 years old) was an independent risk factor for unfavorable short-term neurological outcomes and was mainly associated with the incidence of postoperative severe cerebral infarction.
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