Evidence map›Paper›PMID 33415505›Full record

ArticleNaunyn-Schmiedeberg's archives of pharmacology2021

Prenatal exposure to methamphetamine in rats induces endothelial dysfunction in male but not female adult offspring.

Allison M Harrison, Manoranjan S D'Souza, Sarah L Seeley, Sophocles Chrissobolis

Abstract read
PubMed Publisher
In one paragraph

Article in Naunyn-Schmiedeberg's archives of pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Allison M Harrison *Department of Pharmaceutical and Biomedical Sciences, Raabe College of Pharmacy, Ohio Northern University, 525 S. Main St., Ada, OH, 45810, USA.
Manoranjan S D'Souza *Department of Pharmaceutical and Biomedical Sciences, Raabe College of Pharmacy, Ohio Northern University, 525 S. Main St., Ada, OH, 45810, USA.
Sarah L SeeleyDepartment of Pharmaceutical and Biomedical Sciences, Raabe College of Pharmacy, Ohio Northern University, 525 S. Main St., Ada, OH, 45810, USA.
Sophocles ChrissobolisDepartment of Pharmaceutical and Biomedical Sciences, Raabe College of Pharmacy, Ohio Northern University, 525 S. Main St., Ada, OH, 45810, USA. s-chrissobolis@onu.edu.ORCID 0000-0002-3071-6427
Ohio Northern University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In utero exposure to methamphetamine results in significant developmental, neurological, and behavioral deficits in offspring. However, very little is known about the cardiovascular effects of prenatal methamphetamine exposure in adult offspring. We hypothesized that prenatal methamphetamine exposure causes adverse cardiovascular effects in adult offspring. The aims of this study were to test the effects of prenatal methamphetamine exposure on blood pressure and endothelial function in male and female adult rat offspring. Pregnant rats were injected with methamphetamine (5 mg kg

Indexed as

AnimalsBlood PressureCentral Nervous System StimulantsEndothelium, VascularFemaleMaleMethamphetaminePregnancyPrenatal Exposure Delayed EffectsRatsRats, Sprague-DawleySex FactorsVasodilationCentral Nervous System StimulantsMethamphetamineBlood pressureEndothelial dysfunctionPrenatal methamphetamineSex differencesVascular function

Identifiers

PMID33415505
OpenAlexW3119319647

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.