Evidence map›Paper›PMID 33415488›Full record

SynthesisInternational urology and nephrology2021

Lingual versus buccal mucosal graft for augmentation urethroplasty: a meta-analysis of surgical outcomes and patient-reported donor site morbidity.

Andrew Wang, Michael Chua, Vishal Talla, Nicolas Fernandez, Jessica Ming, Esther May Sarino, Jessica DeLong, Ramón Virasoro, Jeremy Tonkin, Kurt McCammon

Abstract readComparative StudyMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in International urology and nephrology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. [Robot-assisted laparoscopic ureteroplasty with buccal mucosa graft for complex ureteral stricture].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2024
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Andrew WangDepartment of Urology, Eastern Virginia Medical School, Devine-Jordan Center for Reconstructive Surgery and Pelvic Health Urology of Virginia, 225 Clearfield Avenue, Virginia Beach, Norfolk, VA, 23462, USA.
Michael ChuaDepartment of Urology, Eastern Virginia Medical School, Devine-Jordan Center for Reconstructive Surgery and Pelvic Health Urology of Virginia, 225 Clearfield Avenue, Virginia Beach, Norfolk, VA, 23462, USA.
Vishal TallaOld Dominion University, Norfolk, VA, USA.
Nicolas FernandezDivision of Urology, Seattle Children's Hospital, University of Washington, Seattle, WA, USA.
Jessica MingDepartment of Surgery, Urology Division, University of New Mexico, Albuquerque, NM, USA.
Esther May SarinoReference Services, Brickell Medical Science Library, Eastern Virginia Medical School, Norfolk, VA, USA.
Jessica DeLongDepartment of Urology, Eastern Virginia Medical School, Devine-Jordan Center for Reconstructive Surgery and Pelvic Health Urology of Virginia, 225 Clearfield Avenue, Virginia Beach, Norfolk, VA, 23462, USA.
Ramón VirasoroDepartment of Urology, Eastern Virginia Medical School, Devine-Jordan Center for Reconstructive Surgery and Pelvic Health Urology of Virginia, 225 Clearfield Avenue, Virginia Beach, Norfolk, VA, 23462, USA.
Jeremy TonkinDepartment of Urology, Eastern Virginia Medical School, Devine-Jordan Center for Reconstructive Surgery and Pelvic Health Urology of Virginia, 225 Clearfield Avenue, Virginia Beach, Norfolk, VA, 23462, USA.
Kurt McCammonDepartment of Urology, Eastern Virginia Medical School, Devine-Jordan Center for Reconstructive Surgery and Pelvic Health Urology of Virginia, 225 Clearfield Avenue, Virginia Beach, Norfolk, VA, 23462, USA. MccammKA@evms.edu.
Eastern Virginia Medical School · USUrology of Virginia · USOld Dominion University · USSeattle Children's Hospital · USUniversity of New Mexico · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aimed at comparing surgical outcomes and patient-reported donor site morbidity between lingual mucosal graft (LMG) and buccal mucosal graft (BMG) through a meta-analysis of comparative studies.

methodsA systematic literature search was performed in January 2019 including non-randomized comparative studies and randomized controlled trials (RCT). The assessed data included urethroplasty outcomes, complications, and donor site morbidities such as pain, bleeding, swelling, numbness, difficulty speaking, difficulty eating, mouth opening, and difficulty with tongue protrusion.

resultsA total of 632 patients (LMG 323, BMG 309) from 12 comparative studies (four RCTs and eight non-randomized) were included in the meta-analysis. Overall pooled effect estimates revealed no significant difference on reported surgical outcomes and operative stricture-related complications. The LMG group reported a higher proportion of patients with difficulty speaking (RR 6.96, 95% CI 2.04-23.70) and difficulty with tongue protrusion (RR 12.93, 95% CI 3.07-54.51) within 30 days post-op. In comparison, the BMG group had significantly more incidence of early post-procedural donor site swelling (RR 0.39, 95% CI 0.25-0.61) and numbness within 30 days post-op (RR 0.48, 95% CI 0.23-0.97) and 3-6 months (RR 0.52, 95% CI 0.30-0.90) post-op.

conclusionThe evidence suggests no overall significant difference between LMG and BMG with regard to urethroplasty outcomes at 1-year follow-up. While patients undergoing LMG urethroplasty have a higher chance of experiencing difficulty with speech and difficulty with tongue protrusion within 1 month of surgery, the BMG group is more likely to experience early donor site swelling and mouth opening difficulty within 30 days post-op, as well as oral numbness for up to 6 months.

Indexed as

Transplant Donor SiteHumansMaleMouth MucosaPatient Reported Outcome MeasuresPostoperative ComplicationsTongueTreatment OutcomeUrethraUrethral StrictureUrologic Surgical Procedures, MaleAugmentation urethroplastyBuccal mucosaLingual mucosaPatient-reported quality of lifeUrethral stricture

Identifiers

PMID33415488
OpenAlexW3120537957

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.