Evidence map›Paper›PMID 33415394›Full record

ArticleParasitology research2021

The first case of periorbital human dirofilariasis in the Czech Republic.

Jan Gebauer, Jaroslav Ondruš, Pavel Kulich, Ladislav Novotný, Rusłan Sałamatin, Petr Husa, Adam Novobilský

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Parasitology research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Nasolabial dirofilariasis in humans: a case report.Oral and maxillofacial surgery · 2025
    Article
  4. Article
  5. Current State of CanineAnimals : an open access journal from MDPI · 2024
    Article
  6. Pathogens (Basel, Switzerland) · 2021
    Review
  7. A rare subcutaneous periorbital zoonotic infection in a 42-year-old female patient.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Jan GebauerDepartment of Pharmacology and Toxicology, Veterinary Research Institute, Hudcova 296/70, 621 00, Brno, Czech Republic.ORCID https://orcid.org/0000-0002-3167-4695
Jaroslav OndrušDepartment of Pharmacology and Toxicology, Veterinary Research Institute, Hudcova 296/70, 621 00, Brno, Czech Republic.ORCID https://orcid.org/0000-0001-6502-6840
Pavel KulichDepartment of Pharmacology and Toxicology, Veterinary Research Institute, Hudcova 296/70, 621 00, Brno, Czech Republic.
Ladislav NovotnýNovopath s.r.o., Vrchlického 230, 533 45, Čeperka, Czech Republic.ORCID https://orcid.org/0000-0002-2222-1061
Rusłan SałamatinDepartment of General Biology and Parasitology, Medical University of Warsaw, 02-004, Warsaw, Poland.ORCID https://orcid.org/0000-0002-5982-8406
Petr HusaDepartment of Infectious Diseases, University Hospital Brno, Jihlavská 340/20, Brno, Czech Republic.
Adam NovobilskýDepartment of Pharmacology and Toxicology, Veterinary Research Institute, Hudcova 296/70, 621 00, Brno, Czech Republic. novobilsky@vri.cz.ORCID https://orcid.org/0000-0002-0953-0273
Veterinary Research Institute · CZMasaryk University · CZMedical University of Warsaw · PLUniversity Pathologists · US

Funding

Ministerstvo Školství, Mládeže a Tělovýchovy CZ.02.1.01/0.0/0.0/15_003/0000495Ministerstvo Zemědělství MZE-RO0518
6 · The paper itself

Abstract

Dirofilaria repens and Dirofilaria immitis are the most common filarial species affecting humans in Europe. Dirofilaria repens causes subcutaneous or ocular infection, whereas D. immitis is responsible mainly for the pulmonary form. In this report, we present the first human case of periorbital dirofilariasis in the Czech Republic. A 58-year-old woman suffered from an eyelid oedema, redness and pain in the left eye. After excising the parasite from her eyelid, all clinical symptoms disappeared. Based on the morphology and cytochrome oxidase I sequencing, the parasite was identified as D. repens. Histology revealed that the excised worm was female with absent microfilariae in uteri. With respect to the length of the incubation period and the sequence identity with a known Czech isolate, we concluded that D. repens was most likely of autochthonous origin.

Indexed as

AnimalsCyclooxygenase 1Czech RepublicDirofilaria repensDirofilariasisEye Infections, ParasiticFemaleHelminth ProteinsHumansMicrofilariaeMiddle AgedCyclooxygenase 1Helminth ProteinsClinical symptomCytochrome oxidase IDirofilaria repensEyeFilarialHumanMicrofilariaOcular infection

Identifiers

PMID33415394
OpenAlexW3118558818

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.