ArticleCerebral cortex (New York, N.Y. : 1991)2021
Resting State Hypoconnectivity of Reward Networks in Binge Eating Disorder.
Article in Cerebral cortex (New York, N.Y. : 1991), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed.
- The neurobiology of binge eating disorder: a systematic review of studies using functional magnetic resonance imaging.Reviews in endocrine & metabolic disorders · 2026Review
- Altered effective connectivity between the prefrontal cortex and caudate in children with overweight and obesity.International journal of obesity (2005) · 2026Article
- Chronic Co-administration of Methylphenidate and Fluoxetine Reduces Striatal NMDA Receptor Binding in Adolescent Rats.Neurochemical research · 2026Article
- Neurocognitive performance and appetite-regulating hormones in obesity with and without eating disorders: A comprehensive review and empirical analysis.Reviews in endocrine & metabolic disorders · 2026Review
- Peripheral inflammation mediates cognitive deficits in drug-naive schizophrenia through hippocampal-thalamo-visual circuitry dysfunction.Schizophrenia (Heidelberg, Germany) · 2026Article
- Intermittent theta burst stimulation (iTBS) and inhibitory control training to reduce binge eating: study protocol for a randomized controlled trial (Be-Nemoic).Frontiers in psychology · 2026Article
- Multimodal machine learning reveals neurobiological signatures of binge-type eating disorders.Frontiers in neuroscience · 2026Article
- Influence of caloric restriction history, intermittent exposure to palatable food and sex in a binge eating model in C57BL/6J mice.Journal of eating disorders · 2025Article
- Distinct attention network topology and dynamics and their relations with pubertal hormones in preadolescent boys and girls with binge eating.Translational psychiatry · 2025Article
- Mechanism-based subtyping in binge eating: understanding neurobehavioral heterogeneity across negative emotionality, approach behavior, and executive function.Translational psychiatry · 2025Article
- Exploring the neurobiological correlates of psilocybin-assisted psychotherapy in eating disorders: a review of potential methodologies and implications for the psychedelic study design.Journal of eating disorders · 2024Review
- Reward and Inhibitory Control as Mechanisms and Treatment Targets for Binge Eating Disorder.Current psychiatry reports · 2024Review
- Distinct Topological Properties of the Reward Anticipation Network in Preadolescent Children With Binge Eating Disorder Symptoms.Journal of the American Academy of Child and Adolescent Psychiatry · 2024Article
- The emerging role of glucagon-like peptide 1 in binge eating.The Journal of endocrinology · 2024Review
- Temperament impact on eating disorder symptoms and habit formation: a novel model to inform treatment.Journal of eating disorders · 2024Review
- Neuromodulation of Eating Disorders: A Review of Underlying Neural Network Activity and Neuromodulatory Treatments.Brain sciences · 2024Review
- Functional Connectivity Mechanisms Underlying Symptom Reduction Following Lisdexamfetamine Treatment in Binge-Eating Disorder: A Clinical Trial.Biological psychiatry global open science · 2024Article
- Self-objectification and eating disorders: the psychopathological and neural processes from psychological distortion to psychosomatic illness.Psychoradiology · 2024Review
- Back to the future: Progressing memory research in eating disorders.The International journal of eating disorders · 2023Article
- The Role of the Endocannabinoid System in Binge Eating Disorder.International journal of molecular sciences · 2023Review
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
The clinical presentation of binge eating disorder (BED) and data emerging from task-based functional neuroimaging research suggests that this disorder may be associated with alterations in reward processing. However, there is a dearth of research investigating the functional organization of brain networks that mediate reward in BED. To address this gap, 27 adults with BED and 21 weight-matched healthy controls (WMC) completed a multimodel assessment consisting of a resting functional magnetic resonance imaging scan, behavioral tasks measuring reward-based decision-making (i.e., delay discounting and reversal learning), and self-report assessing clinical symptoms. A seed-based approach was employed to examine the resting state functional connectivity (rsFC) of the striatum (nucleus accumbens [NAcc] and ventral and dorsal caudate), a collection of regions implicated in reward processing. Compared with WMC, the BED group exhibited lower rsFC of striatal seeds, with frontal regions mediating executive functioning (e.g., superior frontal gyrus [SFG]) and posterior, parietal, and temporal regions implicated in emotional processing. Lower NAcc-SFG rsFC was associated with more difficulties with reversal learning and binge eating frequency in the BED group. Results suggest that hypoconnectivity of striatal networks that integrate self-regulation and reward processing may promote the clinical phenomenology of BED. Interventions for BED may benefit from targeting these circuit-based disturbances.
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