Evidence map›Paper›PMID 33415103›Full record

ArticleFrontiers in bioengineering and biotechnology2020

Metal Organic Frame-Upconverting Nanoparticle Assemblies for the FRET Based Sensor Detection of Bisphenol A in High-Salt Foods.

Zhou Xu, Lin-Wei Zhang, Ling-Li Long, Shao-Hua Zhu, Mao-Long Chen, Li Ding, Yun-Hui Cheng

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Article in Frontiers in bioengineering and biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

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0cells of the map it votes in
5citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Zhou XuCollege of Chemistry and Food Engineering, Changsha University of Science & Technology, Changsha, China.
Lin-Wei ZhangCollege of Chemistry and Food Engineering, Changsha University of Science & Technology, Changsha, China.
Ling-Li LongCollege of Chemistry and Food Engineering, Changsha University of Science & Technology, Changsha, China.
Shao-Hua ZhuChangsha Customs Technology Center, Changsha Customs District P.R. China, Changsha, China.
Mao-Long ChenCollege of Chemistry and Food Engineering, Changsha University of Science & Technology, Changsha, China.
Li DingCollege of Chemistry and Food Engineering, Changsha University of Science & Technology, Changsha, China.
Yun-Hui ChengCollege of Chemistry and Food Engineering, Changsha University of Science & Technology, Changsha, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To resolve the occurrence of unfulfillable detection in high-salts foods, we used fluorescence resonant energy transfer (FRET) sensors based on nanoparticle upconversion. In this study, we developed a novel FRET sensor for the detection of bisphenol A (BPA) in high-salt foods. We based this approach on the assembly of aptamer modified upconversion nanoparticles (DNA1-UCNPs) and complementary DNA modified metal organic frames (DNA2-MOFs), which possessed corresponding wavelength absorption. Targeting BPA signal transduction was performed using the BPA aptamer, via competitive recognition between the BPA analyte and complementary DNA sequences in a high-salt solution. Sensor adaption in high-salt samples was attributed to functional hydrophilic groups, modified in the MOFs, and the enhanced colloidal stability of these MOFs. The MOF-UCNP assembly displayed considerable analytical performance in terms of BPA detection, with a linear range of 0.1-100 nM, and a limit of detection (LOD) of 0.02 nM, in a 340 mM NaCl food sample (the energy drink, Gatorade). Thus, this method provides a solid basis for small molecules detection in high-salt foods.

Indexed as

aptamerbisphenol Afluorescence resonant energy transferhigh-salt foodsmetal organic frame-upconversion nanoparticle assembly

Identifiers

PMID33415103
PMCPMC7783312

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