Evidence map›Paper›PMID 33415016›Full record

ArticleAmerican journal of cancer research2020

A novel prognostic scoring model for newly diagnosed FLT3-ITD-positive acute myeloid leukemia.

Yi Zhang, Bi-De Zhao, Cheng-Cheng Wang, Yun-Gui Wang, Hua-Feng Wang, Jing-Han Wang, Li-Xia Liu, Feng Lou, Shan-Bo Cao, Xiao-Xia Hu and 7 more

Open access · greenAbstract read
In one paragraph

Article in American journal of cancer research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 2 institutions in 1 country.

Yi ZhangDepartment of Hematology, The First Affiliated Hospital, College of Medicine, Zhejiang University Hangzhou, Zhejiang, China.
Bi-De ZhaoDepartment of Hematology, The Second Affiliated Hospital of Xi'an Jiaotong University Xi'an, Shaanxi, China.
Cheng-Cheng WangAcornmed Biotechnology Co., Ltd. Beijing, China.
Yun-Gui WangDepartment of Hematology, The First Affiliated Hospital, College of Medicine, Zhejiang University Hangzhou, Zhejiang, China.
Hua-Feng WangDepartment of Hematology, The First Affiliated Hospital, College of Medicine, Zhejiang University Hangzhou, Zhejiang, China.
Jing-Han WangDepartment of Hematology, The First Affiliated Hospital, College of Medicine, Zhejiang University Hangzhou, Zhejiang, China.
Li-Xia LiuAcornmed Biotechnology Co., Ltd. Beijing, China.
Feng LouAcornmed Biotechnology Co., Ltd. Beijing, China.
Shan-Bo CaoAcornmed Biotechnology Co., Ltd. Beijing, China.
Xiao-Xia HuDepartment of Hematology, Institute of Hematology, Changhai Hospital Shanghai, China.
Ai-Jie HuangDepartment of Hematology, Institute of Hematology, Changhai Hospital Shanghai, China.
Jian-Min YangDepartment of Hematology, Institute of Hematology, Changhai Hospital Shanghai, China.
Hai-Tao MengDepartment of Hematology, The First Affiliated Hospital, College of Medicine, Zhejiang University Hangzhou, Zhejiang, China.
Wen-Juan YuDepartment of Hematology, The First Affiliated Hospital, College of Medicine, Zhejiang University Hangzhou, Zhejiang, China.
Hong-Yan TongDepartment of Hematology, The First Affiliated Hospital, College of Medicine, Zhejiang University Hangzhou, Zhejiang, China.
Jian-Min WangDepartment of Hematology, Institute of Hematology, Changhai Hospital Shanghai, China.
Jie JinDepartment of Hematology, The First Affiliated Hospital, College of Medicine, Zhejiang University Hangzhou, Zhejiang, China.
Zhejiang University · CNSecond Affiliated Hospital of Xi'an Jiaotong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

FMS-like tyrosine kinase 3-internal tandem duplication (FLT3-ITD) is one of the most common somatic mutations in acute myeloid leukemia (AML). However, the molecular structure characteristics and widely accepted prognostic factors for FLT3-ITD are still not well described. This study aimed to retrospectively examine 81 patients with FLT3-ITD-positive AML diagnosed and treated at the First Affiliated Hospital of Zhejiang University from December 2013 to March 2018 using the next-generation sequencing 185-gene platform. High variant allele frequency (VAF) [> 0.48,

Indexed as

Acute myeloid leukemiaFLT3-ITDLASSO cox regressionnext-generation sequencingprognosis

Identifiers

PMID33415016
PMCPMC7783775
OpenAlexW3120248707

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.