ReviewAmerican journal of cancer research2020
Primary malignant melanomas of the female lower genital tract: clinicopathological characteristics and management.
Review in American journal of cancer research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 28 citations in OpenAlex.
- Multimodal ultrasound imaging in the diagnosis of primary vaginal malignant melanoma: A case report.Medicine · 2026Article
- Exploring the immune landscape of melanoma of the lower female genital tract.Virchows Archiv : an international journal of pathology · 2026Article
- Primary Clitoral Melanoma: Personalized Therapeutic Strategies Informed by Clinical Evidence and Systematic Review.Journal of personalized medicine · 2026Review
- Web-based predictive tool for vaginal and vulvar melanomas: a machine learning study.Future science OA · 2025Article
- Review
- Comparative Insights into Cutaneous, Mucosal, and Vulvovaginal Melanomas: Biology, Targeted Therapies, and Survival with a Focus on Immune Checkpoint Inhibitors.Journal of personalized medicine · 2025Review
- Dermoscopic Features of Vulvar Melanoma.Indian dermatology online journal · 2025Article
- The clinical practice and outcomes of minimally invasive surgery in primary malignant melanoma of the vagina and cervix patients: a retrospective cohort study.Orphanet journal of rare diseases · 2025Article
- The genetic landscape of primary malignant melanoma of the cervix using integrated bioinformatics analysis and whole-exome sequencing.Frontiers in oncology · 2025Article
- Diagnosis and treatment of 33 patients with primary melanoma of the female reproductive system.Frontiers in oncology · 2025Article
- Primary Malignant Melanoma of The Endocervix Uteri and Outpatient Hysteroscopy as a Diagnostic Tool: Case Report and Literature Overview.Diseases (Basel, Switzerland) · 2024Review
- A Rare Case of Invasive Malignant Melanoma Metastasis in the Vulvar Mucosa 11 Years After Diagnosis and Treatment.Cureus · 2024Article
- A case of primary malignant melanoma of the female genital tract involving both the cervix and vagina.Quantitative imaging in medicine and surgery · 2024Article
- Long-term response of vulvar mucosal melanoma treated with neoadjuvant nivolumab.JAAD case reports · 2023Article
- Primary Melanoma of the Cervix Uteri: A Systematic Review and Meta-Analysis of the Reported Cases.Biology · 2023Review
- Case report: a robotic-vaginal approach for total vaginectomy and hysterectomy with pelvic sentinel lymph node dissection in primary vaginal melanoma: a 10-step technique and literature review.Frontiers in surgery · 2023Article
- Gynecologic tract melanoma in the contemporary therapeutic era: High rates of local and distant disease progression.Gynecologic oncology · 2022Article
- Genitourinary melanoma: An overview for the clinician.Asian journal of urology · 2022Review
- Successful treatment of metastatic vulvar malignant melanoma with toripalimab: A rare case report and review of the literature.Medicine · 2022Review
- Vaginal Malignant Melanoma: Case Report and Review of the Literature.European journal of case reports in internal medicine · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The female lower genital tract melanomas mainly include vulvar, vaginal and cervical melanoma. There is little clinical data on the melanomas thus making them highly lethal with their prognosis being worse than for cutaneous melanoma and other gynecological malignancies. Surgery is still the primary treatment for gynecological melanomas with wide local resection (WLE) of tumors with adequate margins being preferred for early-stage vulvar melanoma while complete resection of the primary tumor is the standard treatment for early-stage cervical and vaginal melanoma. Sentinel lymph node biopsy seems to avoid unnecessary complete regional lymphadenectomy. However, it should be chosen cautiously. Recently discovered molecular changes have provided new hopes for effective systemic treatment of female genital tract melanomas. In this review, we summarize the pathogenesis and clinicopathological characteristics of these rare melanomas with particular emphasis on new therapies and clinical management methods that may affect prognosis. The review aims to provide a viable direction for clinicians to diagnose and treat female lower genital tract melanomas.
Indexed as
Identifiers
33414983PMC7783736W3120062250What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.