Evidence map›Paper›PMID 33414852›Full record

ArticleBeilstein journal of organic chemistry2020

Deoxyfluorination of acyl fluorides to trifluoromethyl compounds by FLUOLEAD

Yumeng Liang, Akihito Taya, Zhengyu Zhao, Norimichi Saito, Norio Shibata

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Beilstein journal of organic chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Synthetic Strategies to Access Fluorinated Azoles.European journal of organic chemistry · 2025
    Article
  2. Article
  3. Strengthening of the C-F Bond in Fumaryl Fluoride with Superacids.Chemistry (Weinheim an der Bergstrasse, Germany) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yumeng LiangDepartment of Nanopharmaceutical Sciences, Nagoya Institute of Technology, Gokiso, Showa-ku, Nagoya 466-5888, Japan.ORCID https://orcid.org/0000-0002-2846-0792
Akihito TayaDepartment of Life Science and Applied Chemistry, Nagoya Institute of Technology, Gokiso, Showa-ku, Nagoya 466-5888, Japan.
Zhengyu ZhaoDepartment of Life Science and Applied Chemistry, Nagoya Institute of Technology, Gokiso, Showa-ku, Nagoya 466-5888, Japan.
Norimichi SaitoPharmaceutical Division, Ube Industries, Ltd., Seavans North Bldg, 1-2-1 Shibaura, Minato-ku, Tokyo 105-8449, Japan.
Norio ShibataDepartment of Nanopharmaceutical Sciences, Nagoya Institute of Technology, Gokiso, Showa-ku, Nagoya 466-5888, Japan.ORCID https://orcid.org/0000-0002-3742-4064

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A new protocol enabling the formation of trifluoromethyl compounds from acyl fluorides has been developed. The combination of FLUOLEAD

Indexed as

acyl fluoridesdeoxyfluorinationfluorinesolvent-freetrifluoromethyl group

Identifiers

PMID33414852
PMCPMC7753111

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.