ArticleTherapeutic advances in neurological disorders2020
Sex disparity in long-term stroke recurrence and mortality in a rural population in the United States.
Article in Therapeutic advances in neurological disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 24 citations in OpenAlex.
- Trial
- Association of estimated muscle mass and its changes with all-cause mortality: a Chinese population-based cohort study.BMC geriatrics · 2026Article
- Proteomic and Demographic Comparisons of Recurrent Ischemic Stroke Patients.Translational stroke research · 2025Article
- Gender disparities in all-cause mortality among individuals with early-onset cardiovascular diseases.BMC public health · 2024Article
- Stroke Recurrence Following 28 Days After First Stroke in Men and Women 2012 to 2020: Observations From the Swedish Stroke Register.Journal of the American Heart Association · 2023Article
- Predictors of Post-Stroke Depression: A Retrospective Cohort Study.Brain sciences · 2022Article
- Comparison of Long-Term Outcomes and Associated Factors between Younger and Older Rural Ischemic Stroke Patients.Journal of clinical medicine · 2022Article
- The Impact of Sex and Gender on Stroke.Circulation research · 2022Review
- Analysis of Prognostic Risk Factors for Ischemic Stroke in China: A Multicentre Retrospective Clinical Study; A National Survey in China.Current neurovascular research · 2022Article
- One-year recurrence of stroke and death in Lebanese survivors of first-ever stroke: Time-to-Event analysis.Frontiers in neurology · 2022Article
- Sex differences in the risk of recurrent ischemic stroke after ischemic stroke and transient ischemic attack.European stroke journal · 2021Article
- "Lessons Learned" Preventing Recurrent Ischemic Strokes through Secondary Prevention Programs: A Systematic Review.Journal of clinical medicine · 2021Review
- Predicting short and long-term mortality after acute ischemic stroke using EHR.Journal of the neurological sciences · 2021Article
- Machine Learning-Enabled 30-Day Readmission Model for Stroke Patients.Frontiers in neurology · 2021Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundSeveral studies suggest women may be disproportionately affected by poorer stroke outcomes than men. This study aims to investigate whether women have a higher risk of all-cause mortality and recurrence after an ischemic stroke than men in a rural population in central Pennsylvania, United States.
methodsWe analyzed consecutive ischemic stroke patients captured in the Geisinger NeuroScience Ischemic Stroke research database from 2004 to 2019. Kaplan-Meier (KM) estimator curves stratified by gender and age were used to plot survival probabilities and Cox Proportional Hazards Ratios were used to analyze outcomes of all-cause mortality and the composite outcome of ischemic stroke recurrence or death. Fine-Gray Competing Risk models were used for the outcome of recurrent ischemic stroke, with death as the competing risk. Two models were generated; Model 1 was adjusted by data-driven associated health factors, and Model 2 was adjusted by traditional vascular risk factors.
resultsAmong 8900 adult ischemic stroke patients [median age of 71.6 (interquartile range: 61.1-81.2) years and 48% women], women had a higher crude all-cause mortality. The KM curves demonstrated a 63.3% survival in women compared with a 65.7% survival in men (
conclusionSex was not an independent risk factor for all-cause mortality and ischemic stroke recurrence in the rural population in central Pennsylvania.
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