Evidence map›Paper›PMID 33414838›Full record

ReviewEvidence-based complementary and alternative medicine : eCAM2020

Pharmacological Activity of Eriodictyol: The Major Natural Polyphenolic Flavanone.

Zirong Deng, Sabba Hassan, Muhammad Rafiq, Hongshui Li, Yang He, Yi Cai, Xi Kang, Zhaoguo Liu, Tingdong Yan

Abstract readReview
In one paragraph

Review in Evidence-based complementary and alternative medicine : eCAM, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Phytochemical Characterization ofFood science & nutrition · 2026
    Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Antibacterial activity ofFrontiers in microbiology · 2025
    Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Review
  18. Systems Metabolic Engineering ofJournal of fungi (Basel, Switzerland) · 2024
    Article
  19. Role of SLC7A11/xCT in Ovarian Cancer.International journal of molecular sciences · 2024
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zirong DengSchool of Pharmacy, Nantong University, 19 Qixiu Road, Nantong, Jiangsu 226001, China.
Sabba HassanDepartment of Physiology and Biochemistry, Cholistan University of Veterinary and Animal Sciences (CUVAS), Bahawalpur 63100, Pakistan.
Muhammad RafiqDepartment of Physiology and Biochemistry, Cholistan University of Veterinary and Animal Sciences (CUVAS), Bahawalpur 63100, Pakistan.ORCID https://orcid.org/0000-0001-9686-6551
Hongshui LiThe Second People Hospital of Dezhou, Dezhou 253022, China.
Yang HeBayRay Innovation Center, Shenzhen Bay Laboratory, Shenzhen 518132, China.
Yi CaiCenter of Pharmaceutical Research and Development, Guangzhou Medical University, Guangzhou, Guangdong 511436, China.
Xi KangCenter of Translational Medicine, Chemical Biology Institute, Shenzhen Bay Laboratory, Shenzhen 518132, China.
Zhaoguo LiuSchool of Pharmacy, Nantong University, 19 Qixiu Road, Nantong, Jiangsu 226001, China.ORCID https://orcid.org/0000-0001-6311-8338
Tingdong YanSchool of Pharmacy, Nantong University, 19 Qixiu Road, Nantong, Jiangsu 226001, China.ORCID https://orcid.org/0000-0002-5193-022X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Eriodictyol is a flavonoid that belongs to a subclass of flavanones and is widespread in citrus fruits, vegetables, and medicinally important plants. Eriodictyol has been anticipated to explain the method of its activity via multiple cellular signaling cascades. Eriodictyol is an effective natural drug source to maintain higher health standards due to its excellent therapeutic roles in neuroprotection, cardioprotective activity, hepatoprotective activity, antidiabetes and obesity, and skin protection and having highly analgesic, antioxidant, and anti-inflammatory effects, antipyretic and antinociceptive actions, antitumor activity, and much more. This review aims to highlight the modes of action of eriodictyol against various diseases via multiple cellular signaling pathways.

Identifiers

PMID33414838
PMCPMC7752289

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.