Evidence map›Paper›PMID 33414717›Full record

ArticleFrontiers in pharmacology2020

Adiponectin Interacts

Jiawen Yong, Julia von Bremen, Gisela Ruiz-Heiland, Sabine Ruf

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 23 citations in OpenAlex.

  1. Loss of Stat3 in Prx1Advanced biology · 2025
    Article
  2. Review
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  14. Adiponectin as Well as Compressive Forces RegulateFrontiers in cell and developmental biology · 2021
    Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jiawen YongDepartment of Orthodontics, Faculty of Medicine, Justus Liebig University Giessen, Giessen, Germany.
Julia von BremenDepartment of Orthodontics, Faculty of Medicine, Justus Liebig University Giessen, Giessen, Germany.
Gisela Ruiz-HeilandDepartment of Orthodontics, Faculty of Medicine, Justus Liebig University Giessen, Giessen, Germany.
Sabine RufDepartment of Orthodontics, Faculty of Medicine, Justus Liebig University Giessen, Giessen, Germany.
University of Giessen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Current clinical evidences suggest that circulating Adipokines such as Adiponectin can influence the ratio of orthodontic tooth movement. We aimed to investigate the effect that Adiponectin has on cementoblasts (OCCM-30) and on the intracellular signaling molecules of Mitogen-activated protein kinase (MAPK). We demonstrated that OCCM-30 cells express AdipoR1 and AdipoR2. Alizarin Red S staining revealed that Adiponectin increases mineralized nodule formation and quantitative AP activity in a dose-dependent manner. Adiponectin up-regulates the mRNA levels of

Indexed as

adiponectincementoblastscementogenesisMAPKmigrationproliferation

Identifiers

PMID33414717
PMCPMC7783624
OpenAlexW3114936651

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.