Evidence map›Paper›PMID 33414401›Full record

ArticleBlood cancer journal2021

Loss of PALB2 predicts poor prognosis in acute myeloid leukemia and suggests novel therapeutic strategies targeting the DNA repair pathway.

Antonella Padella, Maria Chiara Fontana, Giovanni Marconi, Eugenio Fonzi, Elisabetta Petracci, Anna Ferrari, Carmen Baldazzi, Cristina Papayannidis, Andrea Ghelli Luserna Di Rorá, Nicoletta Testoni and 4 more

Open access · goldAbstract readLetter
In one paragraph

Article in Blood cancer journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Fanconi Anemia Pathway Genes Advance Cervical CancerFrontiers in cell and developmental biology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 2 countries.

Antonella PadellaIstituto Scientifico Romagnolo per lo Studio e Cura dei Tumori (IRST) IRCCS, Meldola, Italy. antonella.padella@irst.emr.it.ORCID 0000-0001-9991-992X
Maria Chiara FontanaIstituto Scientifico Romagnolo per lo Studio e Cura dei Tumori (IRST) IRCCS, Meldola, Italy.
Giovanni MarconiAzienda Ospedaliero-Universitaria di Bologna, via Albertoni 15, Bologna, Italia, Istituto di Ematologia "Seràgnoli", Dipartimento di Medicina Specialistica, Diagnostica e Sperimentale, Università degli Studi, Bologna, Italia.ORCID 0000-0001-6309-0515
Eugenio FonziIstituto Scientifico Romagnolo per lo Studio e Cura dei Tumori (IRST) IRCCS, Meldola, Italy.ORCID 0000-0001-8389-8220
Elisabetta PetracciIstituto Scientifico Romagnolo per lo Studio e Cura dei Tumori (IRST) IRCCS, Meldola, Italy.
Anna FerrariIstituto Scientifico Romagnolo per lo Studio e Cura dei Tumori (IRST) IRCCS, Meldola, Italy.ORCID 0000-0002-7022-9906
Carmen BaldazziAzienda Ospedaliero-Universitaria di Bologna, via Albertoni 15, Bologna, Italia, Istituto di Ematologia "Seràgnoli", Dipartimento di Medicina Specialistica, Diagnostica e Sperimentale, Università degli Studi, Bologna, Italia.
Cristina PapayannidisAzienda Ospedaliero-Universitaria di Bologna, via Albertoni 15, Bologna, Italia, Istituto di Ematologia "Seràgnoli", Dipartimento di Medicina Specialistica, Diagnostica e Sperimentale, Università degli Studi, Bologna, Italia.
Andrea Ghelli Luserna Di RoráIstituto Scientifico Romagnolo per lo Studio e Cura dei Tumori (IRST) IRCCS, Meldola, Italy.
Nicoletta TestoniAzienda Ospedaliero-Universitaria di Bologna, via Albertoni 15, Bologna, Italia, Istituto di Ematologia "Seràgnoli", Dipartimento di Medicina Specialistica, Diagnostica e Sperimentale, Università degli Studi, Bologna, Italia.
Gastone CastellaniAzienda Ospedaliero-Universitaria di Bologna, via Albertoni 15, Bologna, Italia, Istituto di Ematologia "Seràgnoli", Dipartimento di Medicina Specialistica, Diagnostica e Sperimentale, Università degli Studi, Bologna, Italia.
Torsten HaferlachMLL Munich Leukemia Laboratory, Munich, Germany.
Giovanni MartinelliIstituto Scientifico Romagnolo per lo Studio e Cura dei Tumori (IRST) IRCCS, Meldola, Italy. giovanni.martinelli@irst.emr.it.ORCID 0000-0002-1025-4210
Giorgia SimonettiIstituto Scientifico Romagnolo per lo Studio e Cura dei Tumori (IRST) IRCCS, Meldola, Italy.ORCID 0000-0001-6954-969X
Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori · ITIstituto di Ematologia di Bologna · ITMunich Leukemia Laboratory (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

DNA RepairAdultAgedAged, 80 and overFanconi Anemia Complementation Group N ProteinFemaleGene DeletionHumansLeukemia, Myeloid, AcuteMaleMiddle AgedPolymorphism, Single NucleotidePrognosisYoung AdultFanconi Anemia Complementation Group N ProteinPALB2 protein, human

Identifiers

PMID33414401
PMCPMC7791026
OpenAlexW3119618833

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.