Evidence map›Paper›PMID 33414250›Full record

ArticleDiabetes2021

One in Ten CD8

Teresa Rodriguez-Calvo, Lars Krogvold, Natalie Amirian, Knut Dahl-Jørgensen, Matthias von Herrath

Abstract read
In one paragraph

Article in Diabetes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Review
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  8. Review
  9. How benign autoimmunity becomes detrimental in type 1 diabetes.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  10. Review
  11. Human islet T cells are highly reactive to preproinsulin in type 1 diabetes.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Teresa Rodriguez-CalvoLa Jolla Institute for Immunology, La Jolla, CA teresa.rodriguez@helmholtz-muenchen.de.
Lars KrogvoldDivision of Pediatric and Adolescent Medicine, Faculty of Medicine, Oslo University Hospital, Oslo, Norway.ORCID 0000-0003-1531-8583
Natalie AmirianLa Jolla Institute for Immunology, La Jolla, CA.
Knut Dahl-JørgensenDivision of Pediatric and Adolescent Medicine, Faculty of Medicine, Oslo University Hospital, Oslo, Norway.
Matthias von HerrathLa Jolla Institute for Immunology, La Jolla, CA.ORCID 0000-0002-5211-0485

Funding

Specificity, Phenotype and Function of Pancreatic CD8 T Cells in Human Type 1 DiabetesR01AI092453 · NIAID · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Estefania Quesada Masachs · 2011 to 2026
$5.7M
NIAID NIH HHS R01 AI092453
6 · The paper itself

Abstract

In type 1 diabetes (T1D), a lifelong autoimmune disease, T cells infiltrate the islets and the exocrine pancreas in high numbers. CD8

Indexed as

AdultAutoimmune DiseasesCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesDiabetes Mellitus, Type 1EpitopesFluorescent Antibody TechniqueHumansInsulinInsulin-Secreting CellsPancreasProtein PrecursorsYoung AdultEpitopesInsulinpreproinsulinProtein Precursors

Identifiers

PMID33414250
PMCPMC7897350

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.