Evidence map›Paper›PMID 33414234›Full record

ArticleAJNR. American journal of neuroradiology2021

3D Quantitative Synthetic MRI in the Evaluation of Multiple Sclerosis Lesions.

S Fujita, K Yokoyama, A Hagiwara, S Kato, C Andica, K Kamagata, N Hattori, O Abe, S Aoki

Open access · hybridAbstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Review
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  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Decoding Gray Matter Involvement in Multiple Sclerosis via Imaging.Neuroimaging clinics of North America · 2024
    Review
  11. Article
  12. Article
  13. Thin-slice Two-dimensional T2-weighted Imaging with Deep Learning-based Reconstruction: Improved Lesion Detection in the Brain of Patients with Multiple Sclerosis.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2024
    Article
  14. Article
  15. Review
  16. Article
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

S FujitaFrom the Departments of Radiology (S.F., A.H., S.K., C.A., K.K., S.A.).ORCID 0000-0003-4276-6226
K YokoyamaNeurology (K.Y., N.H.), Juntendo University, Tokyo, Japan.ORCID 0000-0002-0950-1093
A HagiwaraFrom the Departments of Radiology (S.F., A.H., S.K., C.A., K.K., S.A.) a-hagiwara@juntendo.ac.jp.ORCID 0000-0001-5277-3249
S KatoFrom the Departments of Radiology (S.F., A.H., S.K., C.A., K.K., S.A.).ORCID 0000-0003-0000-9550
C AndicaFrom the Departments of Radiology (S.F., A.H., S.K., C.A., K.K., S.A.).ORCID 0000-0002-9339-6950
K KamagataFrom the Departments of Radiology (S.F., A.H., S.K., C.A., K.K., S.A.).ORCID 0000-0001-5028-218X
N HattoriNeurology (K.Y., N.H.), Juntendo University, Tokyo, Japan.ORCID 0000-0002-2034-2556
O AbeDepartment of Radiology (S.F., S.K., O.A.), The University of Tokyo, Tokyo, Japan.ORCID 0000-0002-1180-2629
S AokiFrom the Departments of Radiology (S.F., A.H., S.K., C.A., K.K., S.A.).ORCID 0000-0002-8491-0698
Juntendo University · JPNorwegian Womens Public Health Association · NOUniversity of Tokyo Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeSynthetic MR imaging creates multiple contrast-weighted images based on a single time-efficient quantitative scan, which has been mostly performed for 2D acquisition. We assessed the utility of 3D synthetic MR imaging in patients with MS by comparing its diagnostic image quality and lesion volumetry with conventional MR imaging. MATERIALS AND

methodsTwenty-four patients with MS prospectively underwent 3D quantitative synthetic MR imaging and conventional T1-weighted, T2-weighted, FLAIR, and double inversion recovery imaging, with acquisition times of 9 minutes 3 seconds and 18 minutes 27 seconds for the synthetic MR imaging and conventional MR imaging sequences, respectively. Synthetic phase-sensitive inversion recovery images and those corresponding to conventional MR imaging contrasts were created for synthetic MR imaging. Two neuroradiologists independently assessed the image quality on a 5-point Likert scale. The numbers of cortical lesions and lesion volumes were quantified using both synthetic and conventional image sets.

resultsThe overall diagnostic image quality of synthetic T1WI and double inversion recovery images was noninferior to that of conventional images (

conclusionsThree-dimensional synthetic MR imaging could serve as an alternative to conventional MR imaging in evaluating MS with a reduced scan time.

Indexed as

AdultBrainFemaleHumansImaging, Three-DimensionalMagnetic Resonance ImagingMaleMiddle AgedMultiple Sclerosis

Identifiers

PMID33414234
PMCPMC7959431
OpenAlexW3119354835

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.