Evidence map›Paper›PMID 33413716›Full record

ArticleEpidemiology and psychiatric sciences2021

A Bayesian approach to estimating the population prevalence of mood and anxiety disorders using multiple measures.

Jordan Edwards, A Demetri Pananos, Amardeep Thind, Saverio Stranges, Maria Chiu, Kelly K Anderson

Abstract read
In one paragraph

Article in Epidemiology and psychiatric sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Article
  7. Surveillance of Child and Youth Mental Disorders and Associated Service Use in Canada.Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2023
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jordan EdwardsDepartment of Epidemiology & Biostatistics, The University of Western Ontario, London, Ontario, Canada.ORCID https://orcid.org/0000-0002-1420-3795
A Demetri PananosDepartment of Epidemiology & Biostatistics, The University of Western Ontario, London, Ontario, Canada.
Amardeep ThindDepartment of Epidemiology & Biostatistics, The University of Western Ontario, London, Ontario, Canada.
Saverio StrangesDepartment of Epidemiology & Biostatistics, The University of Western Ontario, London, Ontario, Canada.
Maria ChiuICES, Toronto, Ontario, Canada.
Kelly K AndersonDepartment of Epidemiology & Biostatistics, The University of Western Ontario, London, Ontario, Canada.ORCID https://orcid.org/0000-0001-9843-404X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsThere is currently no universally accepted measure for population-based surveillance of mood and anxiety disorders. As such, the use of multiple linked measures could provide a more accurate estimate of population prevalence. Our primary objective was to apply Bayesian methods to two commonly employed population measures of mood and anxiety disorders to make inferences regarding the population prevalence and measurement properties of a combined measure.

methodsWe used data from the 2012 Canadian Community Health Survey - Mental Health linked to health administrative databases in Ontario, Canada. Structured interview diagnoses were obtained from the survey, and health administrative diagnoses were identified using a standardised algorithm. These two prevalence estimates, in addition to data on the concordance between these measures and prior estimates of their psychometric properties, were used to inform our combined estimate. The marginal posterior densities of all parameters were estimated using Hamiltonian Monte Carlo (HMC), a Markov Chain Monte Carlo technique. Summaries of posterior distributions, including the means and 95% equally tailed posterior credible intervals, were used for interpretation of the results.

resultsThe combined prevalence mean was 8.6%, with a credible interval of 6.8-10.6%. This combined estimate sits between Bayesian-derived prevalence estimates from administrative data-derived diagnoses (mean = 7.4%) and the survey-derived diagnoses (mean = 13.9%). The results of our sensitivity analysis suggest that varying the specificity of the survey-derived measure has an appreciable impact on the combined posterior prevalence estimate. Our combined posterior prevalence estimate remained stable when varying other prior information. We detected no problematic HMC behaviour, and our posterior predictive checks suggest that our model can reliably recreate our data.

conclusionsAccurate population-based estimates of disease are the cornerstone of health service planning and resource allocation. As a greater number of linked population data sources become available, so too does the opportunity for researchers to fully capitalise on the data. The true population prevalence of mood and anxiety disorders may reside between estimates obtained from survey data and health administrative data. We have demonstrated how the use of Bayesian approaches may provide a more informed and accurate estimate of mood and anxiety disorders in the population. This work provides a blueprint for future population-based estimates of disease using linked health data.

Indexed as

AdolescentAnxiety DisordersBayes TheoremCanadaFemaleHealth SurveysHumansMood DisordersPopulation SurveillancePrevalenceBayesian analysisCommon mental disordersdiagnosis and classificationepidemiologyprevalenceresearch design and methods

Identifiers

PMID33413716
PMCPMC8057492

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.