Evidence map›Paper›PMID 33413701›Full record

ArticleEuropean psychiatry : the journal of the Association of European Psychiatrists2021

Identification and management of cardiometabolic risk in subjects with schizophrenia spectrum disorders: A Delphi expert consensus study.

Silvana Galderisi, Marc De Hert, Stefano Del Prato, Andrea Fagiolini, Philip Gorwood, Stefan Leucht, Aldo Pietro Maggioni, Armida Mucci, Celso Arango

Abstract readConsensus Statement
In one paragraph

Article in European psychiatry : the journal of the Association of European Psychiatrists, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

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3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Silvana GalderisiDepartment of Psychiatry, University of Campania Luigi Vanvitelli, Naples, Italy.ORCID 0000-0002-1592-7656
Marc De HertUniversity Psychiatric Centre-KU Leuven, Kortenberg, Belgium.
Stefano Del PratoDepartment of Clinical and Experimental Medicine, Section of Metabolic Diseases and Diabetes, University of Pisa, Pisa, Italy.ORCID 0000-0002-5388-0270
Andrea FagioliniDepartment of Molecular Medicine, Division of Psychiatry, University of Siena, Siena, Italy.
Philip GorwoodINSERM U1266, Institute of Psychiatry and Neurosciences of Paris (IPNP) & GHU Paris Psychiatrie et Neurosciences (CMME, Sainte-Anne Hospital), Université de Paris, Paris, France.ORCID 0000-0003-1845-3676
Stefan LeuchtDepartment of Psychiatry and Psychotherapy, School of Medicine, Technische Universität München, Munich, Germany.ORCID 0000-0002-4934-4352
Aldo Pietro MaggioniMaria Cecilia Hospital, GVM Care & Research, Cotignola, Ravenna, Italy.ORCID 0000-0003-2764-6779
Armida MucciDepartment of Psychiatry, University of Campania Luigi Vanvitelli, Naples, Italy.ORCID 0000-0002-6195-9456
Celso ArangoDepartment of Child and Adolescent Psychiatry, Institute of Psychiatry and Mental Health, Hospital General Gregorio Marañón, IiSGM, School of Medicine, Universidad Complutense, CIBERSAM, Madrid, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients with schizophrenia spectrum disorders (SSD) have worse physical health and reduced life expectancy compared to the general population. In 2009, the European Psychiatric Association, the European Society of Cardiology and the European Association for the Study of Diabetes published a position paper aimed to improve cardiovascular and diabetes care in patients with severe mental illnesses. However, the initiative did not produce the expected results. Experts in SSD or in cardiovascular and metabolic diseases convened to identify main issues relevant to management of cardiometabolic risk factors in schizophrenia patients and to seek consensus through the Delphi method.

methodsThe steering committee identified four topics: 1) cardiometabolic risk factors in schizophrenia patients; 2) cardiometabolic risk factors related to antipsychotic treatment; 3) differences in antipsychotic cardiometabolic profiles; 4) management of cardiometabolic risk. Twelve key statements were included in a Delphi questionnaire delivered to a panel of expert European psychiatrists.

resultsConsensus was reached for all statements with positive agreement higher than 85% in the first round. European psychiatrists agreed on: 1) high cardiometabolic risk in patients with SSD, 2) importance of correct risk management of cardiometabolic diseases, from lifestyle modification to treatment of risk factors, including the choice of antipsychotic drugs with a favourable cardiometabolic profile. The expert panel identified the psychiatrist as the central coordinating figure of management, possibly assisted by other specialists and general practitioners.

conclusionsThis study demonstrates high level of agreement among European psychiatrists regarding the importance of cardiovascular risk assessment and management in subjects with SSD.

Indexed as

Antipsychotic AgentsCardiovascular DiseasesSchizophreniaConsensusHumansRisk FactorsAntipsychotic Agentsantipsychotic cardiometabolic profilecardiometabolic riskDelphi methodmonitoring of cardiometabolic riskschizophrenia spectrum disorderssmoking cessation

Identifiers

PMID33413701
PMCPMC8057390

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.