ArticleCancer imaging : the official publication of the International Cancer Imaging Society2021
Magnetic resonance diffusion kurtosis imaging in differential diagnosis of benign and malignant renal tumors.
Article in Cancer imaging : the official publication of the International Cancer Imaging Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed.
- Motion and Flow Robust Free-Breathing Diffusion Kurtosis Imaging of the Kidney.NMR in biomedicine · 2025Article
- Diffusion kurtosis versus diffusion-weighted magnetic resonance imaging in differentiating clear cell renal cell carcinoma and renal angiomyolipoma with minimal fat: a comparative study.Diagnostic and interventional radiology (Ankara, Turkey) · 2025Article
- Longitudinal multi-b-value diffusion-weighted imaging in renal transplant recipients: diagnostic efficacy and prognostic value for allograft dysfunction.Quantitative imaging in medicine and surgery · 2025Article
- Exploring the value of arterial spin labeling and six diffusion MRI models in differentiating solid benign and malignant renal tumors.European radiology experimental · 2024Article
- Probing Renal Microstructure and Function with Advanced Diffusion MRI: Concepts, Applications, Challenges, and Future Directions.Journal of magnetic resonance imaging : JMRI · 2024Review
- Characteristic Mean Kurtosis Values in Simple Diffusion Kurtosis Imaging of Dentigerous Cysts.Diagnostics (Basel, Switzerland) · 2023Article
- Monoexponential, biexponential, stretched-exponential and kurtosis models of diffusion-weighted imaging in kidney assessment: comparison between patients with primary aldosteronism and healthy controls.Abdominal radiology (New York) · 2023Article
- "To Be or Not to Be Benign" at Partial Nephrectomy for Presumed RCC Renal Masses: Single-Center Experience with 195 Consecutive Patients.Diseases (Basel, Switzerland) · 2023Article
- Evaluation of calculation processes of apparent diffusion coefficient subtraction method (ASM) imaging.PloS one · 2023Article
- Preliminary study on intravoxel incoherent motion imaging and diffusion kurtosis imaging based on magnetic resonance imaging of normal kidneys in children.Translational pediatrics · 2022Article
- Diffusion weighted imaging and diffusion kurtosis imaging in abdominal oncological setting: why and when.Infectious agents and cancer · 2022Review
- MRI-Based Radiomics and Urine Creatinine for the Differentiation of Renal Angiomyolipoma With Minimal Fat From Renal Cell Carcinoma: A Preliminary Study.Frontiers in oncology · 2022Article
- Diffusion kurtosis imaging features of renal cell carcinoma: a preliminary study.The British journal of radiology · 2021Article
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Abstract
backgroundBenign and malignant renal tumors share similar some imaging findings.
methodsSixty-six patients with clear cell renal cell carcinoma (CCRCC), 13 patients with renal angiomyolipoma with minimal fat (RAMF) and 7 patients with renal oncocytoma (RO) were examined. For diffusion kurtosis imaging (DKI), respiratory triggered echo-planar imaging sequences were acquired in axial plane (3 b-values: 0, 500, 1000s/mm
resultsFor MD, a significant higher value was shown in CCRCC (3.08 ± 0.23) than the rest renal tumors (2.93 ± 0.30 for RO, 1.52 ± 0.24 for AML, P < 0.05). The MD values were higher for RO than for AML (2.93 ± 0.30 vs.1.52 ± 0.24, P < 0.05), while comparable MD values were found between CCRCC and RO (3.08 ± 0.23 vs. 2.93 ± 0.30, P > 0.05). For MK, KA and RK, a significant higher value was shown in AML (1.32 ± 0.16, 1.42 ± 0.23, 1.41 ± 0.29) than CCRCC (0.43 ± 0.08, 0.57 ± 0.16, 0.37 ± 0.11) and RO (0.81 ± 0.08, 0.86 ± 0.16, 0.69 ± 0.08) (P < 0.05). The MK, KA and RK values were higher for RO than for CCRCC (0.81 ± 0.08 vs. 0.43 ± 0.08, 0.86 ± 0.16 vs. 0.57 ± 0.16, 0.69 ± 0.08 vs. 0.37 ± 0.11, P < 0.05). Using MD values of 2.86 as the threshold value for differentiating CCRCC from RO and AML, the best result obtained had a sensitivity of 76.1%, specificity of 72.6%. Using MK, KA and RK values of 1.19,1.13 and 1.11 as the threshold value for differentiating AML from CCRCC and RO, the best result obtained had a sensitivity of 91.2, 86.7, 82.1%, and specificity of 86.7, 83.2, 72.8%.
conclusionDKI can be used as another noninvasive biomarker for benign and malignant renal tumors' differential diagnosis.
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