Evidence map›Paper›PMID 33413576›Full record

ArticleScandinavian journal of trauma, resuscitation and emergency medicine2021

Apnoeic oxygenation for emergency anaesthesia of pre-hospital trauma patients.

Kate Crewdson, Ainsley Heywoth, Marius Rehn, Samy Sadek, David Lockey

Open access · goldAbstract read
In one paragraph

Article in Scandinavian journal of trauma, resuscitation and emergency medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. The process of rapid sequence intubation in the prehospital setting: A scoping review.The Southern African journal of critical care : the official journal of the Critical Care Society · 2025
    Review
  5. Article
  6. Article
  7. Rapid sequence induction: where did the consensus go?Scandinavian journal of trauma, resuscitation and emergency medicine · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Kate CrewdsonLondon's Air Ambulance, London, UK. Kate.crewdson@nbt.nhs.uk.ORCID http://orcid.org/0000-0003-4295-6425
Ainsley HeywothEssex & Herts Air Ambulance Trust, Essex, UK.
Marius RehnLondon's Air Ambulance, London, UK.
Samy SadekEssex & Herts Air Ambulance Trust, Essex, UK.
David LockeyLondon's Air Ambulance, London, UK.
Herts and Essex Hospital · GBQueen Mary University of London · GBSouthmead Hospital · GBStiftelsen Norsk Luftambulanse · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEfficient and timely airway management is universally recognised as a priority for major trauma patients, a proportion of whom require emergency intubation in the pre-hospital setting. Adverse events occur more commonly in emergency airway management, and hypoxia is relatively frequent. The aim of this study was to establish whether passive apnoeic oxygenation was effective in reducing the incidence of desaturation during pre-hospital emergency anaesthesia.

methodsA prospective before-after study was performed to compare patients receiving standard care and those receiving additional oxygen via nasal prongs. The primary endpoint was median oxygen saturation in the peri-rapid sequence induction period, (2 minutes pre-intubation to 2 minutes post-intubation) for all patients. Secondary endpoints included the incidence of hypoxia in predetermined subgroups.

resultsOf 725 patients included; 188 patients received standard treatment and 537 received the intervention. The overall incidence of hypoxia (first recorded SpO

conclusionApnoeic oxygenation did not influence peri-intubation oxygen saturations, but it did reduce the frequency and duration of hypoxia in the post-intubation period. Given that apnoeic oxygenation is a simple low-cost intervention with a low complication rate, and that hypoxia can be detrimental to outcome, application of nasal cannulas during the drug-induced phase of emergency intubation may benefit a subset of patients undergoing emergency anaesthesia.

Indexed as

AnesthesiaCannulaEmergency Service, HospitalOxygen Inhalation TherapyWounds and InjuriesAdultAirway ManagementFemaleHumansHypoxiaMaleMiddle AgedProspective StudiesApnoeic oxygenationEmergencyIntubationPre-oxygenationTrauma

Identifiers

PMID33413576
PMCPMC7789511
OpenAlexW3120794838

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.