Evidence map›Paper›PMID 33413560›Full record

ArticleBMC sports science, medicine & rehabilitation2021

Effect of position and exercise on measurement of muscle quantity and quality: towards a standardised pragmatic protocol for clinical practice.

Carly Welch, Zeinab Majid, Isabelle Andrews, Zaki Hassan-Smith, Vicky Kamwa, Hannah Picton, Daisy Wilson, Thomas A Jackson

Open access · goldAbstract read
In one paragraph

Article in BMC sports science, medicine & rehabilitation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Carly WelchMRC-Versus Arthritis Centre for Musculoskeletal Ageing Research, University of Birmingham and University of Nottingham, Birmingham, UK. c.welch@bham.ac.uk.ORCID https://orcid.org/0000-0003-3894-355X
Zeinab MajidInstitute of Inflammation and Ageing, University of Birmingham, Birmingham, B15 2TT, UK.
Isabelle AndrewsInstitute of Inflammation and Ageing, University of Birmingham, Birmingham, B15 2TT, UK.
Zaki Hassan-SmithUniversity Hospitals Birmingham NHS Foundation Trust, Birmingham, B15 2GW, UK.
Vicky KamwaInstitute of Inflammation and Ageing, University of Birmingham, Birmingham, B15 2TT, UK.
Hannah PictonInstitute of Inflammation and Ageing, University of Birmingham, Birmingham, B15 2TT, UK.
Daisy WilsonInstitute of Inflammation and Ageing, University of Birmingham, Birmingham, B15 2TT, UK.
Thomas A JacksonMRC-Versus Arthritis Centre for Musculoskeletal Ageing Research, University of Birmingham and University of Nottingham, Birmingham, UK.
University Hospitals Birmingham NHS Foundation Trust · GBUniversity of Birmingham · GB

Funding

Medical Research Council MR/P021220/1
6 · The paper itself

Abstract

backgroundUltrasonography is an emerging non-invasive bedside tool for muscle quantity/quality assessment; Bioelectrical Impedance Analysis (BIA) is an alternative non-invasive bedside measure of body composition, recommended for evaluation of sarcopenia in clinical practice. We set out to assess impact of position and exercise upon measures towards protocol standardisation.

methodsHealthy volunteers aged 18-35 were recruited. Bilateral Anterior Thigh Thickness (BATT; rectus femoris and vastus intermedius), BATT: Subcutaneous Ratio (BATT:SCR), and rectus femoris echogenicity were measured using ultrasound and BIA was performed; 1) lying with upper body at 45° (Reclined), 2) lying fully supine at 180

resultsForty-four participants (52% female; mean 25.7 years-old (SD 5.0)) were recruited. BATT increased from Reclined to Sitting (+ 1.45 cm, 1.27-1.63), and after exercise (+ 0.51, 0.29-0.73). Echogenicity reduced from Reclined to Sitting (- 2.1, - 3.9 - -0.26). SMM-Sergi declined from Reclined to Supine (- 0.65 kg, - 1.08 - - 0.23) and after exercise (- 0.70 kg, - 1.27 - -0.14). ECW increased from Reclined to Sitting (+ 1.19 L, 0.04-2.35). There were no other statistically significant changes.

conclusionStandardisation of protocols is especially important for assessment of muscle quantity by ultrasonography; BIA measurements may also vary dependent on the equations used. Where possible, participants should be rested prior to muscle ultrasonography and BIA, and flexion of the knees should be avoided.

Indexed as

Diagnostic imagingElectric impedanceMusclesSarcopenia

Identifiers

PMID33413560
PMCPMC7792326
OpenAlexW3119609244

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.