Evidence map›Paper›PMID 33413544›Full record

ReviewChinese medicine2021

Pharmacological activities and mechanisms of action of Pogostemon cablin Benth: a review.

Chen Junren, Xie Xiaofang, Li Mengting, Xiong Qiuyun, Li Gangmin, Zhang Huiqiong, Chen Guanru, Xu Xin, Yin Yanpeng, Peng Fu and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in Chinese medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
6.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 111 citations in OpenAlex.

  1. Article
  2. Review
  3. Prevention and Treatment ofPathogens (Basel, Switzerland) · 2026
    Review
  4. Review
  5. Article
  6. Article
  7. Patchouli alcohol suppressesFrontiers in pharmacology · 2026
    Article
  8. Article
  9. Impact of Dietary Supplementation withAnimals : an open access journal from MDPI · 2025
    Article
  10. Article
  11. Article
  12. Metabolomic Profiling ofInternational journal of molecular sciences · 2025
    Article
  13. Patchouli Ethanol ExtractAging medicine (Milton (N.S.W)) · 2025
    Article
  14. Review
  15. Review
  16. Article
  17. Mediators of inflammation · 2025
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Chen JunrenChengdu University of Traditional Chinese Medicine, Chengdu, 610075, China.
Xie XiaofangChengdu University of Traditional Chinese Medicine, Chengdu, 610075, China.
Li MengtingChengdu University of Traditional Chinese Medicine, Chengdu, 610075, China.
Xiong QiuyunChengdu University of Traditional Chinese Medicine, Chengdu, 610075, China.
Li GangminChengdu University of Traditional Chinese Medicine, Chengdu, 610075, China.
Zhang HuiqiongChengdu University of Traditional Chinese Medicine, Chengdu, 610075, China.
Chen GuanruChengdu University of Traditional Chinese Medicine, Chengdu, 610075, China.
Xu XinChengdu University of Traditional Chinese Medicine, Chengdu, 610075, China.
Yin YanpengChengdu University of Traditional Chinese Medicine, Chengdu, 610075, China.
Peng FuChengdu University of Traditional Chinese Medicine, Chengdu, 610075, China. fujing126@yeah.net.
Peng ChengChengdu University of Traditional Chinese Medicine, Chengdu, 610075, China. pengchengchengdu@126.com.
Chengdu University of Traditional Chinese Medicine · CN

Funding

Fundamental Research Funds for the Central Universities no.YJ201880The Key Project of Science and Technology Department of Sichuan Province no. 20ZDYF3092The major task of the Ministry of Science and Technology for the creation of new drugs of the People's Republic of China, the discovery of innovative drugs and the development of new varieties for the prevention and treatment of drug-resistant bacteria by 2019ZX09721001-008
6 · The paper itself

Abstract

Patchouli ("Guanghuoxiang") or scientifically known as Pogostemon cablin Benth, belonging to the family Lamiaceae, has been used in traditional Chinse medicine (TCM) since the time of the Eastern Han dynasty. In TCM theory, patchouli can treat colds, nausea, fever, headache, and diarrhea. Various bioactive compounds have been identified in patchouli, including terpenoids, phytosterols, flavonoids, organic acids, lignins, glycosides, alcohols, pyrone, and aldehydes. Among the numerous compounds, patchouli alcohol, β-patchoulene, patchoulene epoxide, pogostone, and pachypodol are of great importance. The pharmacological impacts of these compounds include anti-peptic ulcer effect, antimicrobial effect, anti-oxidative effect, anti-inflammatory effect, effect on ischemia/reperfusion injury, analgesic effect, antitumor effect, antidiabetic effect, anti-hypertensive effect, immunoregulatory effect, and others.For this review, we examined publications from the previous five years collected from PubMed, Web of Science, Springer, and the Chinese National Knowledge Infrastructure databases. This review summarizes the recent progress in phytochemistry, pharmacology, and mechanisms of action and provides a reference for future studies focused on clinical applications of this important plant extract.

Indexed as

Biological activitiesMechanismsPatchouli alcoholPogostemon cablin Benth. (patchouli)

Identifiers

PMID33413544
PMCPMC7791836
OpenAlexW3118336507

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.