Evidence map›Paper›PMID 33413520›Full record

ArticleJournal of orthopaedic surgery and research2021

Extracorporeal shock wave therapy for bone marrow edema syndrome in patients with osteonecrosis of the femoral head: a retrospective cohort study.

Wenyi Zhao, Yuan Gao, Shouxiang Zhang, Zhang Liu, Lin He, Dahong Zhang, Wei Li, Qinggang Meng

Open access · goldAbstract read
In one paragraph

Article in Journal of orthopaedic surgery and research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Extracorporeal shock wave therapy (ESWT) for treatment of osteonecrosis of the femoral head: a systematic review and meta-analysis.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2026
    Pooled it
  2. Article
  3. Conservative treatments of bone marrow lesions.Journal of experimental orthopaedics · 2025
    Article
  4. Article
  5. Effects of individual shock wave therapyWorld journal of clinical cases · 2023
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Wenyi ZhaoHarbin Medical University, Harbin, China.
Yuan GaoBone and Joint Surgery Department, Pinghu Hospital Affiliated to Shenzhen University, Shenzhen, China.ORCID http://orcid.org/0000-0003-1072-4072
Shouxiang ZhangBone and Joint Surgery Department, Harbin City Hospital No. 1 Affiliated to Harbin Technical University, Harbin, China.
Zhang LiuBone and Joint Surgery Department, First Hospital of Suihua City, Suihua, China.
Lin HeBone and Joint Surgery Department, First Hospital of Suihua City, Suihua, China.
Dahong ZhangBone and Joint Surgery Department, First Hospital of Suihua City, Suihua, China.
Wei LiBone and Joint Surgery Department, Harbin City Hospital No. 1 Affiliated to Harbin Technical University, Harbin, China. liwei9129@126.com.
Qinggang MengHarbin Medical University, Harbin, China. Mengqinggang2009@126.com.
Suizhou Central Hospital · CNHarbin Medical University · CNHarbin University · CNShenzhen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is now ample evidence suggesting that extracorporeal shock wave therapy (ESWT) can improve hip mobility and reduce pain in patients with osteonecrosis of the femoral head (ONFH). The ability of ESWT to cure bone marrow edema syndrome (BMES) in patients with ONFH, 12 weeks after the initial course of ESWT, needs to be verified further and more relevant clinical research-based evidence should be consolidated. This study aimed to evaluate the efficacy of ESWT for BMES caused by ONFH.

methodsThis retrospective cohort study included 67 patients with BMES caused by ONFH who were participating in a rehabilitation program as outpatients. Before and after ESWT, the area of femoral bone marrow edema was evaluated by magnetic resonance imaging (MRI), and the Harris score and Charnley score were evaluated as hip pain and function indicators.

resultsAfter ESWT, MRI revealed that the area of bone marrow edema decreased from 984.6 ± 433.2 mm

conclusionsThis study demonstrated that ESWT can effectively treat BMES caused by ONFH and can aid in pain relief and functional recovery in patients with ONFH. Thus, ESWT should be included in the classic physical therapy regimen for patients with ONFH and BMES.

Indexed as

Extracorporeal Shockwave TherapyAdultAgedBone Marrow DiseasesEdemaFemaleFemur Head NecrosisHumansMaleMiddle AgedRetrospective StudiesSyndromeTreatment OutcomeBone marrow edema syndromeCharnley scoreExtracorporeal shockwave therapyHarris hip scoreOsteonecrosis of the femoral head

Identifiers

PMID33413520
PMCPMC7791851
OpenAlexW3189947036

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.