Evidence map›Paper›PMID 33413328›Full record

ArticleBMC veterinary research2021

A refined method to monitor arousal from hibernation in the European hamster.

Fredrik A F Markussen, Vebjørn J Melum, Béatrice Bothorel, David G Hazlerigg, Valérie Simonneaux, Shona H Wood

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC veterinary research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Fredrik A F MarkussenArctic Chronobiology and Physiology Research Group, Department of Arctic and Marine Biology, UiT - The Arctic University of Norway, NO-9037, Tromsø, Norway.
Vebjørn J MelumArctic Chronobiology and Physiology Research Group, Department of Arctic and Marine Biology, UiT - The Arctic University of Norway, NO-9037, Tromsø, Norway.
Béatrice BothorelInstitute of Cellular and Integrative Neurosciences, CNRS UPR 3212, University of Strasbourg, Strasbourg, France.
David G HazleriggArctic Chronobiology and Physiology Research Group, Department of Arctic and Marine Biology, UiT - The Arctic University of Norway, NO-9037, Tromsø, Norway.
Valérie SimonneauxInstitute of Cellular and Integrative Neurosciences, CNRS UPR 3212, University of Strasbourg, Strasbourg, France.
Shona H WoodArctic Chronobiology and Physiology Research Group, Department of Arctic and Marine Biology, UiT - The Arctic University of Norway, NO-9037, Tromsø, Norway. shona.wood@uit.no.
UiT The Arctic University of Norway · NOCentre National de la Recherche Scientifique · FRUniversité de Strasbourg · FR

Funding

Norges Forskningsråd Aurora travel awardTromsø forskningsstiftelse TFS2016SHWUniversitetet i Tromsø publication fund
6 · The paper itself

Abstract

backgroundHibernation is a physiological and behavioural adaptation that permits survival during periods of reduced food availability and extreme environmental temperatures. This is achieved through cycles of metabolic depression and reduced body temperature (torpor) and rewarming (arousal). Rewarming from torpor is achieved through the activation of brown adipose tissue (BAT) associated with a rapid increase in ventilation frequency. Here, we studied the rate of rewarming in the European hamster (Cricetus cricetus) by measuring both BAT temperature, core body temperature and ventilation frequency.

resultsTemperature was monitored in parallel in the BAT (IPTT tags) and peritoneal cavity (iButtons) during hibernation torpor-arousal cycling. We found that increases in brown fat temperature preceded core body temperature rises by approximately 48 min, with a maximum re-warming rate of 20.9℃*h

conclusionsWe have used a minimally invasive method to monitor BAT temperature during arousal from hibernation illustrating BAT re-warming significantly precedes core body temperature re-warming, informing future study design on arousal from hibernation. We also showed compromised re-warming from hibernation in an animal with a mass obstructing the lungs and heart, likely leading to inefficient ventilation and circulation.

Indexed as

Adipose Tissue, BrownAnimalsArousalBody TemperatureCricetinaeHibernationMonitoring, PhysiologicPeritoneal CavityRespiratory RateThoraxArousalBrown fatHibernationTorpor

Identifiers

PMID33413328
PMCPMC7791859
OpenAlexW3120204244

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.