ArticleBMC complementary medicine and therapies2021
Green coffee methanolic extract and silymarin protect against CCl4-induced hepatotoxicity in albino male rats.
Article in BMC complementary medicine and therapies, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
15 citing papers in PubMed, 31 citations in OpenAlex.
- Protective Effects of Mango Ginger (Current developments in nutrition · 2026Article
- Evening Primrose Oil Attenuates Liver Injury Induced by Carbon Tetrachloride in Albino Rats Via Improvement of Oxidative Stress and TNF-α: Protective Study.Journal of experimental zoology. Part A, Ecological and integrative physiology · 2026Article
- Article
- Evaluation of hepatoprotective and nephroprotective activities ofBiomedical reports · 2025Article
- A computational study to identify Sesamol derivatives as NRF2 activator for protection against drug-induced liver injury (DILI).Molecular diversity · 2024Article
- Green synthesis, characterization, and hepatoprotective effect of zinc oxide nanoparticles fromHeliyon · 2024Article
- The Protective Effects of Vanillic Acid and Vanillic Acid-Coated Silver Nanoparticles (AgNPs) in Streptozotocin-Induced Diabetic Rats.Journal of diabetes research · 2024Article
- Synthesis, characterization and hepatoprotective effect of silymarin phytosome nanoparticles on ethanol-induced hepatotoxicity in rats.BioImpacts : BI · 2023Article
- Hepatoprotective Effect of Kaempferol: A Review of the Dietary Sources, Bioavailability, Mechanisms of Action, and Safety.Advances in pharmacological and pharmaceutical sciences · 2023Review
- Enhancement of the Protective Activity of Vanillic Acid against Tetrachloro-Carbon (CClMolecules (Basel, Switzerland) · 2022Article
- Evaluation of secondary metabolites of herbal plant extracts as an antiviral effect on infectious bursal disease virus isolates in embryonated chicken eggs.Veterinary world · 2021Article
- Alleviation of Malathion Toxicity Effect byPlants (Basel, Switzerland) · 2021Article
- Comparison between the Antioxidant and Antidiabetic Activity of Fenugreek and Buckthorn in Streptozotocin-Induced Diabetic Male Rats.BioMed research international · 2021Article
- Protective effects ofAvicenna journal of phytomedicineArticle
- Hepatoprotective Effect ofGlobal advances in integrative medicine and healthArticle
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDuring the last few decades, patients worldwide have been interested in using alternative medicine in treating diseases to avoid the increased side effects of chemical medications. Green coffee is unroasted coffee seeds that have higher amounts of chlorogenic acid compared to roasted coffee. Green coffee was successfully used to protect against obesity, Alzheimer disease, high blood pressure and bacterial infection.
methodsThis study aimed to investigate the probable protective activity of the green coffee methanolic extract, silymarin and their combination on CCl
resultsIn the positive control group treated with CCl
conclusionsGreen coffee methanolic extract, silymarin, and their combination succeeded in protecting the male rats against CCl4 hepatotoxicity due to their antioxidant activity. Effect of green coffee methanolic extract mixed with silymarin in G5 was more efficient than that of green coffee methanolic extract in G3 or silymarin in G4.
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