Evidence map›Paper›PMID 33413306›Full record

ReviewBMC endocrine disorders2021

Symptomatic primary hyperparathyroidism in a young woman presenting with multiple skeletal destructions: a case report and review of literature.

Shuai Lu, Maoqi Gong, Yejun Zha, Aimin Cui, Wei Tian, Xieyuan Jiang

Open access · goldAbstract readCase ReportsReview
In one paragraph

Review in BMC endocrine disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Shuai LuDepartment of Orthopedic Trauma, Beijing Jishuitan Hospital, Peking University Fourth School of Clinical Medicine, Beijing, 100035, China.
Maoqi GongDepartment of Orthopedic Trauma, Beijing Jishuitan Hospital, Peking University Fourth School of Clinical Medicine, Beijing, 100035, China.
Yejun ZhaDepartment of Orthopedic Trauma, Beijing Jishuitan Hospital, Peking University Fourth School of Clinical Medicine, Beijing, 100035, China.
Aimin CuiDepartment of General Surgery, Beijing Jishuitan Hospital, Peking University Fourth School of Clinical Medicine, Beijing, China.
Wei TianDepartment of Spine Surgery, Beijing Jishuitan Hospital, Peking University Fourth School of Clinical Medicine, No.31 Xinjiekou E Rd, Xicheng District, Beijing, 100035, China. twspine@163.com.ORCID http://orcid.org/0000-0002-0132-3392
Xieyuan JiangDepartment of Orthopedic Trauma, Beijing Jishuitan Hospital, Peking University Fourth School of Clinical Medicine, Beijing, 100035, China. jxytrauma@163.com.
Peking University · CN

Funding

Beijing Jishuitan Hospital's 'Discipline new star' Plan XKXX201604Beijing Municipal Health Commission BMHC2019-9Beijing Natural Science Foundation L192049
6 · The paper itself

Abstract

backgroundMultiple pathological manifestations are rarely present in patients with primary hyperparathyroidism (PHPT). Here we described a case of a young woman who presented with multiple skeletal destructions and received an unclear diagnosis at several hospitals. CASE PRESENTATION: A 30-year-old woman was admitted to our hospital due to pain in both knees and walking difficulty that lasted for 6 and 2 years, respectively. Her laboratory test results revealed a high parathyroid hormone level (822 pg/ml) and hypercalcemia (2.52 mmol/L) in the blood. Parathyroid imaging revealed a lumpy concentration of radioactive uptake detected at the lower pole in the right lobe of the thyroid, and was nearly 2.2 cm * 2.4 cm in size. Next, the patient was treated with parathyroidectomy that resulted in a significant improvement in physiological and clinical symptoms. Moreover, the skeletal destruction and bone mineral density were significantly improved after a 5-years follow-up period.

conclusionsMultiple skeletal destructions can be caused by PHPT that should be taken into consideration in young patients with complex bone lesions.

Indexed as

Bone DensityAdultBone DiseasesFemaleHumansHyperparathyroidism, PrimaryParathyroidectomyPrognosisCase reportHyperparathyroidismMultiple skeletal destructions

Identifiers

PMID33413306
PMCPMC7791781
OpenAlexW3118760220

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.