Observational studyBMC surgery2021
The assessment of perioperative risk factors of anastomotic leakage after intestinal surgeries; a prospective study.
Observational study in BMC surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 26 citations in OpenAlex.
- Cumulative Surgeon Experience and Anastomotic Leakage After Left-Sided and Segmental Colorectal Resection with Primary Anastomosis: A Seven-Year Single-Center Retrospective Study.Medicina (Kaunas, Lithuania) · 2026Observational
- Quantum machine learning for predicting anastomotic leak: a clinical study.Scientific reports · 2026Article
- Determinants of surgical management outcomes among adult patients with intestinal obstruction at Mzuzu central hospital, Malawi.BMC surgery · 2025Article
- Utilizing machine learning approaches to investigate the relationship between cystatin C and serious complications in esophageal cancer patients after esophagectomy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Observational
- Predictors of Colorectal Resection and Primary Anastomosis outcome at Muhimbili National Hospital.The East African health research journal · 2024Article
- Risk factors for leak after omentopexy for duodenal ulcer perforations.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2023Article
- Prevalence and risk factors for early medical and surgical complications following an admission for acute severe ulcerative colitis.Therapeutic advances in gastroenterology · 2023Article
- Asymmetric figure-of-eight single-layer suture technique for intestinal anastomosis: A preliminary study.Frontiers in surgery · 2023Article
- An alternative asymmetric figure-of-eight single-layer suture technique for bowel anastomosis in anFrontiers in surgery · 2022Article
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Authors and funding
15 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAnastomotic leaks (AL) are among the most serious complications due to the substantial impact on the quality of life and mortality. Inspite of the advance in diagnostic tools such as laboratory tests and radiological adjuncts, only moderate improvement has been recorded in the rate of detected leaks. The purpose of the research was to assess the perioperative risk factors for AL.
methodsThis study was achieved at MUH and MIH/Egypt within the period between January 2016 and January 2019 for the candidates who underwent bowel anastomosis for small intestinal (except duodenal one) and colorectal pathology. The collected data were analyzed using SPSS of V-26.
resultsThis study included 315 cases, among them, 27 cases (8.57%) developed AL. The percentage of covering stoma was significantly higher in the non-leakage group vs leakage one (24.3% vs 11.1% respectively). lower albumin, operative timing, perforation, and covering stoma were shown as significant risk factors for leakage, but with multivariate analysis for these factors, the emergency operation, and serum albumin level was the only independent risk factors that revealed the significance consequently (p = 0.043, p = 0.015). The analysis of different predictors of AL on the third day showed that the cut-off point in RR was 29 with 83% sensitivity and 92% specificity in prediction of leakage, the cut-off point in RR was 118 with 74% sensitivity and 87% specificity in prediction of leakage and the cut-off point in CRP was 184.7 with 82% sensitivity and 88% specificity in prediction of AL and all had statistically significant value.
conclusionsThe preoperative serum albumin level and the emergency operations are independent risk factors for anastomotic leakage. Moreover, leakage should be highly suspected in cases with rising respiratory rate, heart rate, and CRP levels.
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