ArticleBMC pediatrics2021
Clinical aspects for differential diagnosis of Kawasaki disease shock syndrome: a case control study.
Article in BMC pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Kawasaki Disease Shock Syndrome vs Classical Kawasaki Disease: A Meta-analysis and Comparison With SARS-CoV-2 Multisystem Inflammatory Syndrome.The Canadian journal of cardiology · 2021Pooled it
- Clinical Features in Children With Kawasaki Disease Shock Syndrome: A Systematic Review and Meta-Analysis.Frontiers in cardiovascular medicine · 2021Pooled it
- Comparison of Clinical Features and Inflammatory Markers between Kawasaki Disease Shock Syndrome and Kawasaki Disease without Shock: A Meta-Analysis.Journal of healthcare engineering · 2021Pooled it
- The expression of C-reactive protein, erythrocyte sedimentation rate, and procalcitonin in children with Kawasaki disease and their correlation with coronary artery ectasia.BMC pediatrics · 2026Article
- Emergency in pediatric rheumatology: a narrative review.Frontiers in medicine · 2026Review
- Predictive value of serum lipid for kawasaki disease shock syndrome: a prospective study.Immunologic research · 2025Article
- Risk factors and an early predictive model for Kawasaki disease shock syndrome in Chinese children.Italian journal of pediatrics · 2024Article
- An early predictive model for Kawasaki disease shock syndrome in children in central China.Frontiers in cardiovascular medicine · 2024Article
- Comparison of COVID-19-associated multisystem inflammatory syndrome in children (MIS-C) and Kawasaki disease shock syndrome: case reports and literature review.Journal of rheumatic diseases · 2023Article
- Similarities and Differences between Multisystem Inflammatory Syndrome in Children (MIS-C) and Kawasaki Disease Shock Syndrome.Children (Basel, Switzerland) · 2023Article
- Comparison of Characteristics and Outcomes of Multisystem Inflammatory Syndrome, Kawasaki Disease and Toxic Shock Syndrome in Children.Medicina (Kaunas, Lithuania) · 2023Observational
- Platelet and ferritin as early predictive factors for the development of macrophage activation syndrome in children with Kawasaki disease: A retrospective case-control study.Frontiers in pediatrics · 2023Article
- Acute Appendicitis as the Initial Presentation of Kawasaki Disease Shock Syndrome in Children.Children (Basel, Switzerland) · 2022Article
- Kawasaki disease in children younger than 6 months of age: characteristics of a Spanish cohort.European journal of pediatrics · 2022Article
- Kawasaki Shock Syndrome with Initial Presentation as Neck lymphadenitis: A Case Report.Children (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBecause of the absence of a specific diagnostic test and pathognomonic clinical features, physicians must rely on the presence of specific clinical criteria and laboratory data that support the diagnosis of KD. To help clinicians distinguish KD, KDSS, septic shock, and TSS earlier, we suggest differential diagnosis and treatment guideline.
methodsMedical records of immunocompetent patients who were admitted to the pediatric department with a diagnosis of KDSS, septic shock or TSS (SS group) were retrospectively reviewed. In addition, KD patients were selected by seasonal matching to each case of KDSS patient by date of admission (± 2 weeks).
resultsThere were 13 patients with KDSS, 35 patients with SS group, and 91 patients with KD. In comparison between KDSS and septic shock group, KDSS group had significantly higher rate of coronary aneurysm incidence, and higher left ventricle dysfunction rate. In comparison between KDSS and TSS, patients with KDSS had a significantly higher erythrocyte sedimentation rate (ESR) and significantly lower creatinine. Receiver operation characteristic curve revealed that the optimal ESR cut off value for determining the KDSS was 56.0 (sensitivity 75.0%, specificity of 100.0%) and the optimal creatinine cut off value for determining the TSS was 0.695 (sensitivity 76.9%, specificity 84.6%).
conclusionsClinical symptoms, laboratory finding, echocardiography, and culture studies can be used to differentiate KD, KDSS, septic shock and TSS.
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