Evidence map›Paper›PMID 33413144›Full record

Trial reportBMC geriatrics2021

The impact of additional resistance and balance training in exercise-based cardiac rehabilitation in older patients after valve surgery or intervention: randomized control trial.

Egle Tamulevičiūtė-Prascienė, Aurelija Beigienė, Mark James Thompson, Kristina Balnė, Raimondas Kubilius, Birna Bjarnason-Wehrens

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC geriatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04234087 (Feasibility and Effectiveness of an Additional Resistance and Balance Training in Cardiac Rehabilitation of Older Patients After Valve Surgery or Intervention), which is not on this map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
5.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04234087 nacompletednot on this map

Feasibility and Effectiveness of an Additional Resistance and Balance Training in Cardiac Rehabilitation of Older Patients After Valve Surgery or Intervention

TypeinterventionalSponsorLithuanian University of Health SciencesRan2018 to 2020Enrolled116ConditionsFrailty Syndrome, Quality of Life, Valve Heart DiseaseArmsAdditional balance and resistance training
3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 51 citations in OpenAlex.

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  19. An Overview of Sport Participation and Exercise Prescription in Mitral Valve Disease.Journal of cardiovascular development and disease · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Egle Tamulevičiūtė-PrascienėRehabilitation Department, Lithuanian University of Health Sciences, Eiveniu g. 2, LT-50161, Kaunas, Lithuania. egle.tamuleviciute-prasciene@lsmuni.lt.ORCID 0000-0001-8495-7595
Aurelija BeigienėRehabilitation Department, Lithuanian University of Health Sciences, Eiveniu g. 2, LT-50161, Kaunas, Lithuania.
Mark James ThompsonUniversity of Zurich, Rämistrasse 71, CH-8006, Zürich, Switzerland.
Kristina BalnėFaculty of Medicine, Lithuanian University of Health Sciences, A. Mickevičiaus g. 9, LT-44307, Kaunas, Lithuania.
Raimondas KubiliusRehabilitation Department, Lithuanian University of Health Sciences, Eiveniu g. 2, LT-50161, Kaunas, Lithuania.
Birna Bjarnason-WehrensInstitute of Cardiology and Sports Medicine, Department of Preventive and Rehabilitative Sport and Exercise Medicine, German Sport University Cologne, Am Sportpark Muengersdorf 6, 50933, Cologne, Germany.
Lithuanian University of Health Sciences · LTGerman Sport University Cologne · DEUniversity of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo evaluate the short- and mid-term effect of a specially tailored resistance and balance training provided in addition to usual cardiac rehabilitation (CR) care program in older patients after valve surgery/intervention.

methodsSingle-center (inpatient CR clinic in Lithuania) randomized controlled trial. Two hundred fifty-two patients were assessed for eligibility on the first day of admittance to CR early after (14.5 ± 5.9 days) valve surgery/intervention between January 2018 and November 2019. Participants were coded centrally in accordance with randomization 1:1 using a computerized list. Control group (CG) patients were provided with usual care phase-II-CR inpatient multidisciplinary CR program, while intervention group (IG) patients received additional resistance and balance training (3 d/wk). Patients participated in a 3-month follow-up. Main outcome measures were functional capacity (6 min walk test (6MWT, meters), cardiopulmonary exercise testing), physical performance (Short Physical Performance Battery (SPPB, score) and 5-m walk test (5MWT, meters/second)), strength (one repetition maximum test for leg press), physical frailty (SPPB, 5MWT).

resultsOne hundred sixteen patients (76.1 ± 6.7 years, 50% male) who fulfilled the study inclusion criteria were randomized to IG (n = 60) or CG (n = 56) and participated in CR (18.6 ± 2.7 days). As a result, 6MWT (IG 247 ± 94.1 vs. 348 ± 100.1, CG 232 ± 102.8 vs. 333 ± 120.7), SPPB (IG 8.31 ± 2.21 vs. 9.51 ± 2.24, CG 7.95 ± 2.01 vs. 9.08 ± 2.35), 5MWT (IG 0.847 ± 0.31 vs. 0.965 ± 0.3, CG 0.765 ± 0.24 vs 0.879 ± 0.29) all other outcome variables and physical frailty level improved significantly (p < 0.05) in both groups with no significant difference between groups. Improvements were sustained over the 3-month follow-up for 6MWT (IG 348 ± 113 vs. CG 332 ± 147.4), SPPB (IG 10.37 ± 1.59 vs CG 9.44 ± 2.34), 5MWT (IG 1.086 ± 0. 307 vs CG 1.123 ± 0.539) and other variables. Improvement in physical frailty level was significantly more pronounced in IG (p < 0.05) after the 3-month follow-up.

conclusionExercise-based CR improves functional and exercise capacity, physical performance, and muscular strength, and reduces physical frailty levels in patients after valve surgery/intervention in the short and medium terms. SPPB score and 5MWT were useful for physical frailty assessment, screening and evaluation of outcomes in a CR setting. Additional benefit from the resistance and balance training could not be confirmed.

trial registrationNCT04234087 , retrospectively registered 21 January 2020.

Indexed as

Cardiac RehabilitationAgedExerciseExercise TestExercise TherapyFemaleHumansMaleMuscle StrengthCardiac rehabilitationExercise trainingPhysical frailtyTAVIValve surgery

Identifiers

PMID33413144
PMCPMC7792183
OpenAlexW3119941030

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.