Evidence map›Paper›PMID 33412988›Full record

ArticleJournal of intensive care medicine2022

Predicting Failure of Non-Invasive Ventilation With RAM Cannula in Bronchiolitis.

Mia Maamari, Gustavo Nino, James Bost, Yao Cheng, Anthony Sochet, Matthew Sharron

Open access · greenAbstract read
In one paragraph

Article in Journal of intensive care medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Mia MaamariDivision of Critical Care Medicine, 12334Children's National Health System, Washington, DC, USA.ORCID https://orcid.org/0000-0002-0118-1638
Gustavo NinoDivision of Pulmonology, 12334Children's National Health System, Washington, DC, USA.
James BostDivision of Biostatistics and Study Methodology, 12334Children's National Health System, Washington, DC, USA.
Yao ChengDivision of Biostatistics and Study Methodology, 12334Children's National Health System, Washington, DC, USA.
Anthony SochetDivision of Anesthesia and Critical Care Medicine, 1500Johns Hopkins All Children's Hospital, St. Petersburg, FL, USA.
Matthew SharronDivision of Critical Care Medicine, 12334Children's National Health System, Washington, DC, USA.
Children's National · USJohns Hopkins University · US

Funding

THE HUMAN INFANT AIRWAY EPITHELIUM AND RECURRENT WHEEZING AFTER RV AND RSV INFECTIONR01HL141237 · NHLBI · CHILDREN'S RESEARCH INSTITUTE · PI NINO, GUSTAVO · 2019 to 2022
$2.8M
Imaging biomarkers of severe respiratory infections in premature infants Phase IIR42HL145669 · NHLBI · KITWARE, INC. · PI ENQUOBAHRIE, ANDINET ASMAMAW, LINGURARU, MARIUS GEORGE · 2021 to 2022
$1.7M
Exosomal miR-155 regulates airway epithelial immune responses in infants with rhinovirus infectionR21AI130502 · NIAID · CHILDREN'S RESEARCH INSTITUTE · PI NINO, GUSTAVO · 2017 to 2018
$495k
TSLP responses in the human infant airway epithelium and recurrent wheezing after RV and RSV InfectionR56HL141237 · NHLBI · CHILDREN'S RESEARCH INSTITUTE · PI NINO, GUSTAVO · 2018 to 2018
$442k
Imaging Biomarkers of Severe Respiratory Infections in Premature InfantsR41HL145669 · NHLBI · KITWARE, INC. · PI ENQUOBAHRIE, ANDINET ASMAMAW, LINGURARU, MARIUS GEORGE · 2018 to 2018
$225k
NHLBI NIH HHS R01 HL141237NHLBI NIH HHS R41 HL145669NHLBI NIH HHS R42 HL145669NHLBI NIH HHS R56 HL141237NIAID NIH HHS R21 AI130502
6 · The paper itself

Abstract

introductionIn infants hospitalized for bronchiolitis on non-invasive ventilation (NIV) via the RAM cannula nasal interface, variables predicting subsequent intubation, or NIV non-response, are understudied. We sought to identify predictors of NIV non-response.

methodsWe performed a retrospective cohort study in infants admitted for respiratory failure from bronchiolitis placed on NIV in a quaternary children's hospital. We excluded children with concurrent sepsis, critical congenital heart disease, or with preexisting tracheostomy. The primary outcome was NIV non-response defined as intubation after a trial of NIV. Secondary outcomes were vital sign values before and after NIV initiation, duration of NIV and intubation, and mortality. Primary analyses included Chi-square, Wilcoxon rank-sum, student's

resultsOf 138 infants studied, 34% were non-responders. There were no differences in baseline characteristics of responders and non-responders. HR decreased after NIV initiation in responders (156 [143-156] to149 [141-158],

conclusionIn children with acute bronchiolitis who fail to respond to NIV and require subsequent intubation, we noted associations with persistently elevated HR after NIV initiation and concurrent bacterial pneumonia.

Indexed as

BronchiolitisNoninvasive VentilationRespiratory InsufficiencyCannulaHumansRetrospective Studiesbronchiolitisintubationnoninvasive ventilationphysiological variabilitypneumoniarespiratory insufficiency

Identifiers

PMID33412988
PMCPMC8886620
OpenAlexW3119877590

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.