Evidence map›Paper›PMID 33412954›Full record

ArticleIntegrative cancer therapies

Dynamic Effects of CAM Techniques on Inflammation and Emotional States: An Integrative Single-Case Study on a Breast Cancer Survivor.

Christian Schubert, Michaela Ott, Julian Hannemann, Magdalena Singer, Harald R Bliem, Kurt Fritzsche, Christina Burbaum, Emil Chamson, Dietmar Fuchs

Abstract readCase Reports
In one paragraph

Article in Integrative cancer therapies. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Christian SchubertClinic for Medical Psychology, Medical University Innsbruck, Innsbruck, Austria.ORCID 0000-0001-7100-0663
Michaela OttInstitute of Psychology, University of Innsbruck, Innsbruck, Austria.
Julian HannemannInstitute of Psychology, University of Innsbruck, Innsbruck, Austria.
Magdalena SingerDepartment of Medical Psychology, Center for Public Health, Medical University of Vienna, Vienna, Austria.
Harald R BliemInstitute of Psychology, University of Innsbruck, Innsbruck, Austria.
Kurt FritzscheDepartment of Psychosomatic Medicine and Psychotherapy, Medical Center, University of Freiburg, Freiburg, Baden-Württemberg, Germany.
Christina BurbaumDepartment of Psychosomatic Medicine and Psychotherapy, Medical Center, University of Freiburg, Freiburg, Baden-Württemberg, Germany.
Emil ChamsonDepartment of Translation Studies, University of Innsbruck, Innsbruck, Austria.
Dietmar FuchsSection for Biological Chemistry, Biocenter of the Medical University Innsbruck, Innsbruck, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study on a breast cancer survivor investigated how episodic practice of various complementary and alternative medicine (CAM) techniques affected the dynamics of emotional states and urinary neopterin-an inflammation marker.

methodsThe 49-year-old female patient (diagnosis: ductal breast carcinoma 5 years before study start, suffering from chronic fatigue and depression) collected her entire urine in 12-hour intervals (from about 8 a.m. to 8 p.m. and from about 8 p.m. to 8 a.m.) for 28 days. The resulting 55 consecutive urine samples were analyzed for neopterin and creatinine levels using HPLC. Also in 12-hour intervals, the patient filled out questionnaires on emotional states and everyday routine, including CAM practice. Weekly, she was interviewed to identify emotionally meaningful everyday incidents, including use of CAM techniques. Time series analysis consisted of ARIMA modeling and cross-correlational analyses.

resultsQualitative evaluation revealed that, with the exception of Tai Chi, all CAM techniques, that is, Jin Shin Jyutsu, music, physiotherapy and energy healing, were experienced as positive. Cross-correlational analyses showed that practice of such CAM techniques was followed first by significant (

conclusionCyclic psychophysiological response patterns following CAM practice were attributable to biopsychosocial feedback mechanisms involving personally meaningful experiences. As lower neopterin levels following CAM point to a health-promoting effect, the patient of this study may have actively contributed to her healing process through episodic CAM practice.

Indexed as

Breast NeoplasmsCancer SurvivorsEmotionsFemaleHumansInflammationMiddle AgedSurveys and QuestionnairesSurvivorsbreast cancerCAMinflammationpsychoneuroimmunologystress

Identifiers

PMID33412954
PMCPMC7797599

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.